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Acceptor splice site --- The boundary between the 3’ end of an intron and the 5’ end of the following exon. Also called 3’ splice site.剪接受体位点：内含子3′末端与下一个外显子5′端之间的交界处。又称3′剪接位点。Acrocentric --- A type of chromosome with the centromere near one end. The human acrocentric chromosomes (13, 14, 15, 21, and 阅读全文
posted @ 2011-05-29 19:48
emanlee
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Relative risk --- A comparison of the risk for a disease or trait in individuals who share a particular factor (such as genotype, an environmental exposure, or a drug) versus the risk among individuals who lack the factor. Affected Unaffected TotalFactor present a b a+bFactor absent c d c+dTotal a+c 阅读全文
posted @ 2011-05-29 19:47
emanlee
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Spectral karyotyping (SKY) --- A procedure that uses the fluorescence in situ hybridization (FISH) technique to stain each of the 24 human chromosomes distinctively.图谱核型分析（SKY）：用荧光原位杂交（FISH）技术，对 24条人类染色体进行各自染色。Splicing --- The splicing out of introns and splicing together of exons in the generation 阅读全文
posted @ 2011-05-29 19:47
emanlee
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Pharmacodynamics --- The effects of a drug or its metabolites on physiological function and metabolic pathways.药效学：药物或其代谢物在生理功能和代谢途径中的作用Pharmacogenetics --- The area of biochemical genetics concerned with the impact of genetic variation on drug response and metabolism.药物遗传学：主要研究遗传因素对物种内不同个体的药物吸收、分布、 阅读全文
posted @ 2011-05-29 19:46
emanlee
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Microarray --- Miniaturized wafer (“chip”) made of glass, plastic, or silicon onto which a large number of different nucleic acids have been individually spotted. See also CGH, expression profile.微阵列：点阵分布有大量核苷酸的微小芯片。参见CGH，表达谱。Microdeletion --- A chromosomal deletion that is too small to be seen unde 阅读全文
posted @ 2011-05-29 19:44
emanlee
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Immunoglobulin gene superfamily --- A family of evolutionarily related genes composed of human leukocyte antigen (HLA) class I and class II genes, immunoglobulin genes, T-cell receptor genes, and other genes encoding cell surface molecules.免疫球蛋白基因超级家族：进化上同源的基因家族，包括HLA I类和II类基因、免疫球蛋白基因、T细胞受体基因以及其它编码细 阅读全文
posted @ 2011-05-29 19:43
emanlee
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Gene flow --- Gradual diffusion of genes from one population to another across a barrier. The barrier may be physical or cultural and may be breached by migration or mixing.基因流：由于合子或配子的散布，基因从某一群体扩散到其它群体，从而引起等位基因频率改变的现象。Gene map --- The characteristic arrangement of the genes on the chromosomes. 基因图： 阅读全文
posted @ 2011-05-29 19:42
emanlee
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Deformation syndrome --- A recognizable pattern of dysmorphic features caused by extrinsic factors that affect the fetus in utero.变形综合征：子宫中因外部因素影响胎儿而导致的一种畸形。Degeneracy of the code --- The genetic code is described as degenerate because most of the 20 amino acids are specified by more than 1 of the 6 阅读全文
posted @ 2011-05-29 19:41
emanlee
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CG (or CpG) island --- Any region of the genome containing an unusually high concentration of the dinucleotide sequence 5’-CG-3’. Often associated with promoters of genes, in particular housekeeping genes.CG（或CpG）岛：含双核苷酸序列5’-CG-3’较多的区域。通常与基因（尤其是持家基因）的启动子有关。CGH --- See comparative genome hybridizatio 阅读全文
posted @ 2011-05-29 19:40
emanlee
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1、数学：高数（上册，下册）、线代、概率论、随机过程，离散数学；2、生物：普通生物学、生物化学、分子生物学、细胞生物学、遗传学、基因组学、蛋白组学等；3、计算机：计算机基础、C语言、C++、JAVA、Perl、数据结构、数据库、数据挖掘、计算机算法、软件工程。这是最基本的，根据方向还有其他很多要学习的。 阅读全文
posted @ 2011-05-29 19:28
emanlee
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