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A gene string can be represented by an 8-character long string, with choices from 'A''C''G', and 'T'.

Suppose we need to investigate a mutation from a gene string startGene to a gene string endGene where one mutation is defined as one single character changed in the gene string.

  • For example, "AACCGGTT" --> "AACCGGTA" is one mutation.

There is also a gene bank bank that records all the valid gene mutations. A gene must be in bank to make it a valid gene string.

Given the two gene strings startGene and endGene and the gene bank bank, return the minimum number of mutations needed to mutate from startGene to endGene. If there is no such a mutation, return -1.

Note that the starting point is assumed to be valid, so it might not be included in the bank.

 

Example 1:

Input: startGene = "AACCGGTT", endGene = "AACCGGTA", bank = ["AACCGGTA"]
Output: 1

Example 2:

Input: startGene = "AACCGGTT", endGene = "AAACGGTA", bank = ["AACCGGTA","AACCGCTA","AAACGGTA"]
Output: 2

 

Constraints:

  • 0 <= bank.length <= 10
  • startGene.length == endGene.length == bank[i].length == 8
  • startGeneendGene, and bank[i] consist of only the characters ['A', 'C', 'G', 'T'].

 

ChatGPT's Solution:

from collections import deque


class Solution:
    def minMutation(self, startGene: str, endGene: str, bank: List[str]) -> int:
        if endGene not in bank:
            return -1
        
        bank = set(bank)  # Convert list to set for O(1) lookup
        queue = deque([(startGene, 0)])  # (current_gene, mutation_steps)
        possible_chars = {'A', 'C', 'G', 'T'}

        while queue:
            current_gene, steps = queue.popleft()
            if current_gene == endGene:
                return steps
            
            for i in range(len(current_gene)):
                for char in possible_chars:
                    if char != current_gene[i]:  # Change one character
                        mutated_gene = current_gene[:i] + char + current_gene[i+1:]
                        if mutated_gene in bank:
                            queue.append((mutated_gene, steps + 1))
                            bank.remove(mutated_gene)  # Avoid revisiting
        
        return -1  # No valid mutation sequence found

 

 

posted on 2025-03-31 11:39  ZhangZhihuiAAA  阅读(8)  评论(0)    收藏  举报