基因功能

Apoptosis Panel for Monitoring Cell Programmed Death and Survival:
TNF Ligand Family:
LTA, LTB, TNF, TNFSF4, TNFSF5, TNFSF6, TNFSF7, TNFSF8, TNFSF9, TNFSF10, TNFSF11, TNFSF12, TNFSF13, TNFSF13B, TNFSF14, TNFSF15, TNFSF18. TNF Receptor Family:
LTBR, TNFRSF1A, TNFRSF1B, TNFRSF4, TNFRSF5, TNFRSF6, TNFRSF6B, TNFRSF7, TNFRSF8, TNFRSF9, TNFRSF10A, TNFRSF10B, TNFRSF10C, TNFRSF10D, TNFRSF11A, TNFRSF11B, TNFRSF12, TNFRSF14, TNFRSF17, TNFRSF18, TNFRSF21.
Bcl-2 Family: BAD, BAG1, BAG3, BAG4, BAK1, BAX, BBC3, BCL2, BCL2A1, BCL2L1, BCL2L11, BCL2L2, BIK, BLK, BNIP3, BOK, HRK, MCL1.
Caspase Family: CASP1, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CASP10, CASP13, CASP14.
IAP Family: BIRC1, BIRC2, BIRC3, BIRC4, BIRC5, BIRC6.
TRAF Family: TANK, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, TRIP. CARD Family: APAF1, ASC, BCL10, NOD1, RIPK2.
Death Domain Family: CRADD, DAPK2, FADD, MYD88, RIPK1.
Death Effector Domain Family: BFAR, CASP8AP2, CFLAR, FADD.
CIDE Domain Family: CIDEA, CIDEB, DFFA, DFFB.
p53 and ATM Pathway: ATM, CHEK1, CHEK2, GADD45A, MDM2, RPA3, TP53, TP73L..

Cell Cycle Panel for Monitoring Proliferation / Carcinogenesis and Growth Arrest / Senescence:
Cell Division Cycle Proteins and Kinases:
CDC2, CDC6, CDC7, CDC16, CDC20, CDC25A, CDC25B, CDC25C, CDC27, CDC34, CDC37, CDC45L, CKS1, CKS2.
Cyclins, Cyclin-Dependent Kinases and Inhibitors:
CCNA1, CCNA2, CCNB1, CCNB2, CCNC, CCND1, CCND2, CCNE1, CCNE2, CCNF, CCNG1, CCNG2, CCNH, CDK2, CDK4, CDK6, CDK7, CDK8, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN2D.
Cyclin and Kinase Inhibitor Degradation:
CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, RBX1, SKP1A, SKP2.
DNA Damage Checkpoint / p53 and ATM Pathways:
ABL1, APAF1, ATM, BAP1, BAX, BCL2, BRCA1, CHEK1, CHEK2, GADD45A, HUS1, MDM2, MRE11A, MRE11B, NBS1, RAD9, RAD17, RAD50, RAD51, RPA3, TIMP3, TP53, UBE1, UBE3A, UBL1.
DNA Replication, Transcriptional Control and Others:
E2F1, E2F2, E2F3, E2F4, E2F5, E2F6, FOXM1, MAD2L1, MAD2L2, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MKI67, PCNA, PRC1, RB1, RBL1, RBL2, TFDP1, TFDP2.

Stress & Toxicity Panel for Monitoring the Type of Stress Induced: Oxidative & Metabolic Stress:
CAT, CRYAB, CYP1A1, CYP1B1, CYP2E, CYP7A1, CYP7B1, EPHX2, FMO1, FMO5, GPX1, GSR, GSTM3, HMOX1, HMOX2, MT1A, MT2A, MT1H, POR, PTGS2, SOD1, SOD2.
Heat Shock & Related Stress:
DNAJA1, DNAJB4, HSF1, HSP105B, HSPA1A, HSPA1B, HSPA1L, HSPA2, HSPA4, HSPA5, HSPA6, HSPA8, HSPA9B, HSPB1, HSPCA, HSPCB, HSPD1, HSPE1. DNA Damage & Repair Stress: ATM, CHEK2, DDB1, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, RAD50, UGT1A9, UNG, XRCC1, XRCC2, XRCC3, XRCC4, XRCC5. Inflammation Stress: BCL3, BCL6, CCL3, CCL4, CCL21, CSF2, CXCL10, IL1A, IL1B, IL6, IL18, LTA, MIF, NFKB1, NOS2A, SERPINE1.

TNF Ligand Family:
LTA (TNF-), LTB (LT-), TNF (TNF-), TNFSF4 (OX40 Ligand), TNFSF5 (CD40 Ligand), TNFSF6 (FasL), TNFSF7 (CD27 Ligand), TNFSF8 (CD30 Ligand), TNFSF9 (4-1BB Ligand), TNFSF10 (TRAIL), TNFSF11 (TRANCE), TNFSF12 (Apo3L), TNFSF13 (APRIL), TNFSF14 (HVEM-L);
TNF Receptor Family:
LTBR, TNFRSF1A (TNFR1), TNFRSF1B (TNFR2), TNFRSF4 (OX40), TNFRSF5 (CD40), TNFRSF6 (Fas), TNFRSF7 (CD27), TNFRSF8 (CD30), TNFRSF9 (4-1BB), TNFRSF10A (DR4), TNFRSF10B (DR5), TNFRSF10C (DcR1), TNFRSF10D (DcR2), TNFRSF12 (DR3), TNFRSF14 (HVEM);
Bcl-2 Family:
BAD, BAK1, BAX, BCL2, BCL2A1 (bfl-1), BCL2L1 (bcl-x), BCL2L11 (bim-like protein), BCL2L2 (bcl-w), BIK, BLK, BNIP3 (nip3), BOK (Mtd), HRK, MCL-1;
Caspase Family:
CASP1, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CASP10, CASP13, CASP14;
IAP Family:
BIRC1 (NIAP), BIRC2 (IAP2), BIRC3 (IAP1), BIRC4 (XIAP), BIRC5 (Survivin), BIRC6 (Bruce);
TRAF Family:
TANK (I-TRAF), TRAF1, TRAF2, TRAF3 (CRAF1), TRAF4, TRAF5, TRAF6, TRIP;
CARD Family:
APAF1, ASC, BCL10 (HuE10), NOD1 (CARD4), NOL3 (Nop30), RIPK2 (CARDIAC);
Death Domain Family:
CRADD, DAPK2, FADD, MYD88, RIPK1;
Death Effector Domain Family:
CASP8AP2 (FLASH), CFLAR (CASPER), FADD, LOC51283 (BAR);
CIDE Domain Family:
CIDEA, CIDEB, DFFA, DFFB;
p53 and ATM Pathway:
ATM, CHEK1 (chk1), CHEK2 (chk2, Rad53), GADD45A, MDM2, P63, RPA3, TP53 (p53)

G1 Phase:
CCND1 (cyclin D1), CCND2 (cyclin D2), CCND3 (cyclin D3), CCNE1 (cyclin E1), CCNE2 (cyclin E2), CDC7L1, CDC34, CDC37, CDK2, CDK4, CDK6, CDKN1A (p21), CDKN1B (p27), CDKN1C (p57), CDKN2A (p16), CDKN2B (p15), CDKN2C (p18), CDKN2D (p19), CKS1, CKS2, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, E2F1, E2F2, E2F3, E2F4, E2F5, E2F6, NEDD8, RB1, RBL1 (p107 RB), RBL2 (p130 RB2), SKP1A, SKP2, TFDP1 (DP1), TFDP2 (DP2);
S Phase:
CCNA1 (cyclin A1), CCNA2 (cyclin A2), CCNC (cyclin C), CCNG1 (cyclin G1), CCNG2 (cyclin G2), CCNH (cyclin H), CDC25A, CDC45L, CDC6, CDK7, CDK8, MCM2, MCM3, MCM4 (CDC21), MCM5 (CDC46), MCM6 (Mis5), MCM7 (CDC47), MKI67 (Ki67), PCNA;
G2 Phase:
CCNB1 (cyclinB1), CCNB2 (cyclin B2), CCNF (cyclin F);
M Phase:
CDC2 (CDK1), CDC16, CDC20 (p55cdc), CDC27, FOXM1 (MPP2), MAD2L1, MAD2L2, PRC1, RBX1;
DNA Damage Checkpoint / p53 and ATM Pathways:
ABL1 (c-Abl), APAF1, ATM, BCL2, BAX, BRCA1, CHEK1 (chk1), CHEK2 (chk2, Rad53), GADD45A, HUS1, MDM2, MRE11A, MRE11B, NBS1 (nibrin), RAD9, RAD17, RAD50, RAD51, RPA3, TIMP3, TP53 (p53), UBC (ubiquitin C), UBE1, UBE3A (E6-AP), UBL1 (SUMO-1)

Specific Promoters and Inhibitors:
AMOT (KIAA1071/angiomotin), ANG (angiogenin), ANGPT1 (angiopoietin-1), ANGPT2 (angiopoietin-2), CHGA (vasostatin);
Growth Factors and Receptors:
Ephrin Family Members:
EFNA2 (Ephrin A2), EFNA5 (Ephrin A5), EFNB2 (Ephrin B2), EPHB4 (Ephrin B4); Fibroblast Growth Factors & Receptors:
FGF1 (aFGF), FGF2 (bFGF), FGF4, FGF6, FGF7, FGFR1, FGFR2 (KGFR), FGFR3, FGFR4;
Platelet-derived Growth Factors & Receptors:
PDGFA, PDGFB, PDGFRA, PDGFRB, PF4 (Platelet factor 4);
Transforming Growth Factors & Receptors:
TGFA, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, TGFBR3;
Vascular Endothelial Growth Factors & Receptors:
FIGF (VEGFD), FLK1 (KDR), FLT1 (VEGFR2), PGF, VEGF, VEGFB, VEGFC;
Others:
CD36, EDG1, EGF, EGFR, GRO1, HGF (Scatter factor), IGF1, TEK (Tie-2), TIE; Cytokines and Chemokines:
CSF3, IFNA1, IFNB1, IFNG, IL10, IL12A, IL8, MDK, NRP1 (neuropilin-1), PRL (prolactin), PTN (pleiotrophin), SCYA2, SPARC, TNFA, TNFSF15 (VEGI);
Adhesion Molecules:
CDH5 (VE-Cadherin), ITGA5 (integrin 5), ITGAV (integrin V), ITGAV (integrin V), ITGB3, PECAM1;
Matrix Proteins, Proteases and Inhibitors:
ADAMTS1 (METH1), ADAMTS8 (METH2), COL18A1 (LOC51695 /endostatin), FN1 (fibronectin), HPSE (heparanase), MMP2, MMP9, MSR1, PLAU (uPA), SERPINB5 (maspin), SERPINF1 (PEDF), THBS1, THBS2, THBS3, THBS4, TIMP1, TIMP2; Transcription Factors:
ERBB2, ETS1, HIF1A, ID1, ID3, MADH1 (SMAD1);
Other Related Genes:
ENG (endoglin), F2 (thrombin), NOS3, PTGS1 (cox-1), PTGS2 (cox-2), RSN (restin), SPP1 (osteopontin)

Growth Factors and Receptors:
CSF1 (csf-1), CSF1R (c-fms/MC-SF-R), FGF1 (a-FGF), FGF2 (b-FGF2), HGF (Scatter factor), IGF2, NGFB, PDGFA, TGFA (TGF-), TGFB1 (TGF-1), VEGF, VEGFC; Cell-Cell and Cell-Matrix Interaction Molecules:
CAV1 (caveolin-1), CDH1 (cadherin-1/ E-cadherin), COL4A2 (collagen 2(IV)), ICAM5 (telencephalin), ITGA2, ITGA3, ITGA5, ITGA6, ITGB1, ITGB3, LAMB1 (laminin 1), LAMC1 (laminin 2), MICA (MUC-18), MUC1, NCAM1, PECAM1, VTN (vitronectin); Metastasis-Associated Proteases:
Matrix Metalloproteinases:
MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP13, MMP14, MMP15, MMP16;
Others:
CASP8, CASP9, CST3 (cystatin C), CTSB (cathepsin B), CTSD (cathepsin D), CTSL (cathepsin L), ELA2 (elastase), HPSE (heparanase), MGEA5 (meningioma hyaluronidase 5), PLAU (uPA), TMPRSS4;
Protease Inhibitors:
SERPINB2 (PAI-2), SERPINB5 (maspin), SERPINE1 (PAI-1), THBS1, THBS2, TIMP1, TIMP2, TIMP3;
Signal Transduction Molecules:
LIMK1 (LIM kinase), PLAUR (uPAR), PIK3C2B, RAC1
Oncogenes:
ERBB2 (c-erb-2/neu), ETS1 (c-ets-1), ETS2 (c-ets-2), ETV4 (PEA3), FES, FOS (c-fos), HRAS (c-hRas), MDM2, MYC (c-myc), RAF1, SRC (c-src);
Metastasis Suppressors: BRMS1 (BrMS1), CD44, DCC, KAI1, KISS1 (KiSS-1), MAP2K4 (mkk4 (JNKK1), MTA1, NM23A (NM23), NME4, PTEN;
Other Related Genes:
API5 (apoptosis inhibitor 5), ARHC (Rho C), EHM2, ENPP2 (autotaxin/ ATX), MGAT3 (acetylglucosaminyltransferase III), MGAT5 (acetylglucosaminyltransferase V), ODC1, PTGS2 (cox-2), S100A4 (mts-1), SNCG (BCSG1), SPP1 (osteopontin)

Apoptosis:
Anti-Apoptosis (18):
AKT1, BCL2, BRAF, CCL2, FOXO1A, HDAC1, IER3, IGF1R, MYBL2, NFKB1, NOTCH2, PEA15, RELA, SEMA4D, TGFB1, TNF, TNFRSF6, VHL.
Caspase Activation (4):
F2R, STAT1, TNFRSF10A, TNFRSF10B.
DNA damage response, signal transduction resulting in induction of apoptosis (3):
ABL1, TP53, TP73.
Factors involved In other aspect of apoptosis (24):
BRCA1, E2F1, FASTK, IL1B, RAF1, RIPK1, SIVA, TNFRSF1A, TNFRSF1B, TNFSF7, TP53BP2, TRADD, BAX, BCL2, F2R, IER3, NFKB1, PEA15, TNF, TNFRSF10A, TNFRSF10B, TNFRSF6, TP53, TP73.
Induction of apoptosis (8):
DCC, NME3, BAX, NOTCH2, TNFRSF10A, TNFRSF10B, TNFRSF6, TRADD.
Induction of apoptosis by signals: intracellular and extracellular, by death domain, and by hormones (10):
BTK, TIMP3, BAX, FASTK, SIVA TP53, CDKN1A, CUL1, TNFRSF10A, TNFRSF10B. Regulation of apoptosis (6): BAX, BCL2, BRCA1, PEA15, TNFRSF10B, TNFRSF6. Others (apoptogenic cytochrome c release channel activity, apoptotic mitochondrial changes, apoptotic program):
VDAC1, BAX, VDAC1.
Cell Cycle:
Cell Cycle Arrest (13):
CGRRF1, MYC, PA2G4, TBRG4, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2D, CUL1, MAPK12, NOTCH2.
Cell Cycle Checkpoint (4):
RB1, BRCA1, CDKN2A, TP53.
Factors involved In other aspect of cell cycle (29):
ATM, CCND1, CCND2, CCND3, CCNE1, CDC20, CDK4, CDK5, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2D, CHAF1A, E2F3, MAPK12, MAPK13, MCM2, PLK2, RBBP4, RBL2, SEPT6, TAF1, TFDP1, TFDP2, CDKN1A, CUL1, E2F1, TP53BP2. Regulation of cell cycle (81):
APC, ING1, KLK10, MCC, MSH2, NF1, NF2, NME1, NME2, PTCH, PTEN, RAP1A, WT1, ATM, BAX, BRCA1, CDKN1C, CDKN2A, CDKN2B, CDKN2D, DCC, MAPK12, RB1, RBL2, TP53, TP73, VHL, AXL, BRCA2, CDC25A, CDC25B, CDK9, CDKL1, CLK1, CSK, E2F5, FRAP1, GSPT1, IFITM1, KRAS2, LCK, MAPRE1, NRAS, PCNA, PCTK1, PCTK2, PDGFA, PDGFB, PIK3CB, PTMA, PTN, SFN, TGFA, VEGF, WEE1, ABL1, APC, ATM, BCL2, CCND1, CCND2, CCND3, CCNE1, CDC20, CDK4, CDKN1A, CDKN1B, E2F1, E2F3, F2R, IGF1R, IL1B, MYBL2, RAP1A, RB1, STAT1, TFDP1, TFDP2, TGFB1, TP53BP2, VHL.
Cell Growth and Differentiation (167):
Cell Differentiation/ Cell Fate Determination (6):
NOTCH1, NOTCH4, NRG1, SKI, SKIL, NOTCH2.
Cell Growth and/or Main-tenance (63):
ABL1, ABL2, ARHGEF5, AXL, BCL2, BRAF, CBFB, CCND1, CDK4, CSF1R, DEK, ETV1, ETV6, FES, FGFR1, FGR, FOS, FOXO1A, GNAS, IER3, IGFBP3, IGFBP4, IGFBP5, JUN, KIT, KRAS2, LCK, LYN, MAP3K8, MAS1, MDM2, MET, MLLT3, MYB, MYC, MYCN, NF1, NFKB2, NOTCH2, NPM1, NRAS, PDGFA, PDGFB, PHB, PIM1, RAF1, RARA, RARB, REL, RET, RHOA, RHOB, RHOC, SEMA3C, SKI, SKIL, SMO, SRC, TGFB1, VEGF, WNT1, WNT3, YES1.
Cell Proliferation (41):
CDC25, CCYR61, EGFR, ERBB2, ERBB4, GAS6, HDGF, KITLG, LRPAP1, MT3, OSM, PDGFRA, TGFBI, CDC25A, CDK4, CDK5, CDK9, CLK1, CSF1R, E2F1, FES, GSPT1, IGFBP4, IL1B, MAPRE1, MAS1, MET, MYC, PA2G4, PCNA, PDGFA, PDGFB, PTCH, PTN, RAF1, SFN, TFDP1, TGFA, TGFB1, NFSF7, VEGF.
Growth Factors (11):
GDF15, HDGF, IL1B, KITLG, NRG1, PDGFA, PDGFB, PTN, TGFA, TGFB1, VEGF. Regulation of Cell Proliferation, Differentiation, Growth, and Volume (46):
BCL2, BRCA1, CAPN1, CAPNS1, CDC25B, CDC2L5, CDK10, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2D, CGRRF1, CLNS1A, CUL1, CYR61, DLG3, FOSL1, IFITM1, IGF1R, IGFBP3, IGFBP4, IGFBP5, IL1B, MDM2, MDM4, MT3, NF1, NF2, NME1, NME2, NOTCH2, NOTCH4, OSM, PTN, RBBP4, SOCS1, SOCS3, TBRG4, TGFBR2, TIMP1, TOB1, TSG101, VEGF, VHL.
Cell Motility:
Cell Migration and Motility (10):
FN1, GNA13, HMMR, NEO1, RAC1, SPINT2, STAT3, THBS1, TPBG, F2R.
Cell-Cell Adhesion (2):
CD44, ICAM1.
Cell-matrix adhesion (6):
ILK, ITGA3, ITGA6, ITGB4, NID, CD44.
Metalloendopeptidases (MMPs) and MMP inhibitors (10):
ACY1, ANPEP, MME, MMP1, MMP14, MMP17, MMP2, PA2G4, TIMP1, TIMP3.
Signal Transduction:
Cell surface receptor linked signal transduction (13):
CBLB, CD59, FZD2, FZD5, FZD9, MYD88, STC1, CCL2, FGFR1, IFITM1, PDGFA, PDGFRA, SMO.
Frizzled and Frizzled-2 Signaling Pathways (9):
DVL1, DVL3, TLE1, FZD9, WNT2, WNT2B, WNT5A, WNT1, WNT3.
G-protein coupled receptor protein signaling pathway (17):
CRHR1, GNB2, GPR39, NMBR, PIK3CG, RGS19, AKT1, CCL2, F2R, FZD2, FZD5, FZD9, GNA13, GNAS, MAS1, PIK3CB, SMO.
Insulin receptor signaling pathway (2):
PDPK1, IGF1R.
integrin-mediated signaling pathway (4):
ILK, ITGA3, ITGA6, ITGB4.
Intracellular Signaling Cascade (29):
FKBP8, GRB2, JAK1, PRKAR1A, RASGRF1, SHB, STAT2, STAT5B, ZAP70, ABL1, ABL2, BRAF, BTK, CBLB, CSK, DVL1, DVL3, FES, FGR, LCK, LYN, RAC1, RAF1, SOCS1, SOCS3, SRC, STAT1, STAT3, YES1.
JAK-STAT Cascade (6):
CCL2, SOCS1, STAT1, STAT2, STAT3, STAT5B.
Notch signaling pathway (2):
NOTCH2, NOTCH4.
RAS protein signal transduction (3):
GRB2, LCK, NF1.
Rho protein signal transduction (4):
ARHGAP5, RHOD, RHOA, RHOB.
Small GTPase mediated signal transduction (13):
ACK1, RAB5A, SIAH2, KRAS2, NRAS, RAC1, RAP1A, RASGRF1, RGS19, RHOA, RHOB, RHOC, RHOD.
Wnt receptor signaling pathway (16)
CSNK1G2, CTNNB1, FRZB, TCF7L2, APC, DVL1, DVL3, FZD2, FZD5, FZD9, TLE1, WNT1, WNT2, WNT2B, WNT3, WNT5A.
Other Cancer-Related Genes (188):
AARS, ABCB1, ABCC4, ABI2, ACP2, ADSL, AK1, AKR1C2, ALB, ANXA5, ANXA7, AP2M1, ARID4A, ASNS, ATF4, ATP5B, ATP5O, BARD1, BHLHB2, BLMH, CANX, CAP1, CAV1, CCT5, CD24, CEBPG, CENPC1, CIB1, CKMT1, CLK2, CLK3, CLTC, COL1A1, COL6A3, COX6C, COX7A2, CRAT, CTNNA1, CTPS, CTSC, CTSD, DCN, DDX10, DHCR7, DHRS2, DHX8, EGR1, EIF5, EPHA2, ERBB3, ERCC3, ETV3, FBN1, FBN2, FOSL2, FOXG1A, FTL, G22P1, GCN5L2, GNB2L1, GSK3A, GTF2I, HPRT1, HRB, HSPA4, HSPA5, HSPA8, HSPB1, HSPH1, HYAL1, HYOU1, ID1, ID2, IDUA, IGF2R, IRF3, JARID1A, JUNB, JUND, K-ALPHA-1, KPNA2, KRT18, KRT2A, KRT9, LAMB1, LAMP2, LCN2, LEP, LITAF, LTF, LZTR1, MADH1, MAP2K2, MAPKAPK3, MARS, MCM4, MGST1, MICB, MNDA, MSH6, MYBL1, MYCL1, MYL9, MYLK, NINJ1, NQO1, NR1D1, NR2F1, NR2F6, NSEP1, PABPC1, PCTK3, PFDN4, PFDN5, PGAM1, PIK3CA, PKM2, PKMYT1, PPARD, PPARG, PPIH, PPP1CA, PPP2R5A, PRDX2, PRDX4, PRKCBP1, PRNP, PRSS15, PSMA1, PTGS1, PTPRN, RAD50, RALBP1, REA, RELB, RFC2, RPN2, RPS6KB1, RRM1, SARS, SELENBP1, SEPP1, SERPINH1, SFPQ, SFRS7, SHH, SLC16A1, SLC1A4, SLC20A1, SMPD1, SNAI2, SND1, SNRPB2, SOD1, SORT1, SPRY2, SRPX, TBL3, TCF1, TFAP2C, TGFBR3, TIE, TJP1, TK1, TNK1, TP53I3, TPT1, TRAM1, TRRAP, TUFM, TXNRD1, TYRO3, UBC, UBE2L6, UCHL1, USP7, VIL2, XRCC1, YWHAB, YWHAZ, ZNF9.

Cell cycle control & DNA Damage Repair:
ATM, BRCA1, BRCA2, CCND1 (cyclin D1), CCNE1 (cyclin E1), CDC25A, CDK4, CDKN1A (p21Waf1), CDKN1B (p27Kip1), CDKN2A (p16Ink4), CHEK2 (chk2/Rad53), MDM2, PRKDC (DNA-PK), RB1, TP53 (p53);
Apoptosis and Cell Senescence:
APAF1, BAD, BAX, BCL2, BCL2L1 (bcl-X), BIRC5 (Survivin), CASP8, CASP9, CFLAR (CASPER), TERT (telomerase), TNFRSF1A (TNF- receptor), TNFRSF6 (Fas), TNFRSF10B (DR5), TNFRSF12 (DR3);
Signal Transduction Molecules and Transcription Factors:
AKT1, CTNNB1 (-catenin), ERBB2, ETS2, FOS, JUN, MAPK14 (p38 MAPK), MAP2K1 (MEK), MYC, NFKB1 (NFB), NFKBIA (IB), PIK3CB (PI3K p110), PIK3R1 (PI3K p85 ), RAF1, RASA1, SRC;
Adhesion:
CD44, CDH1 (E-cadherin), ICAM1, ITGA1 (integrin 1), ITGA2 (integrin 2), ITGA3 (integrin 3), ITGA4 (integrin 4), ITGA5 (integrin 5), ITGA6 (integrin 6), ITGAV (integrin V), ITGB1 (integrin 1), ITGB3 (integrin 3), ITGB5 (integrin 5), MICA (MUC18), NCAM1;
Angiogenesis:
ANGPT1 (angiopoietin-1), ANGPT2 (angiopoietin-2), COL18A1 (endostatin), EGF, EGFR, FGF2 (bFGF), FGFR2, FLT1 (VEGFR), HGF, IFNA1 (IFN), IFNB1 (IFN ), IGF1, IL8, PDGFA, PDGFB, TEK (tie-2), TGFB1, TGFBR1 (ALK-5), THBS1 (thrombospondin-1), THBS2 (thrombospondin-2), TNF, VEGF;
Invasion and metastasis:
KISS1, KAI1, MMP1 (collagenase-1), MMP2 (gelatinase A), MMP9 (gelatinase B), MTA1, NME4 (Nm23), PLAU, PLAUR, SERPINB2 (PAI2), SERPINB5 (maspin), SERPINE1 (PAI1), TIMP1

Androgen Pathway:
CDK2, CDKN1A (p21Waf1/p21Cip1), EGFR, FOLH1, KLK2 (hGK2), KLK3 (PSA), TMEPAI.
Cox-2 Pathway:
FOS, HSPA4 (hsp70), MCL1, PPARG, PTGS2 (Cox-2), TNFRSF10B (DR5).
DNA Damage / p53 Pathways:
BAX, BCL2, CDKN1A (p21Waf1/p21Cip1), GADD45A (gadd45), HIF1A, HSPA4 (hsp70), IGFBP3, MDM2, PIG3, TNFRSF6 (Fas), TNFRSF10B (TrailR/DR5), TRAF1, WIG1. Estrogen Pathway:
BCL2, BRCA1, CTSD (cathepsin D), EGFR, PGR (PR), ZNF147 (Efp).
Hedgehog Pathway:
BMP2, BMP4, EN1 (engrailed), HHIP, FOXA2 (HNF3B), PTCH, PTCH2, WNT1, WNT2, WSB1.
Hypoxia Pathway:
ADRA1B, CDKN1A, EDN1, EPO, HK1, HMOX1 (HO-1), IGFBP3, NOS2A (iNOS), SLC2A1, TF, TFRC, VEGF.
Inflammation / NFkB Pathways: ICAM1, IL2, LTA (TNFb), NFKB1 (NFkB), NFKBIA (IkBa), NOS2A (iNOS), PECAM1, TNF (TNFa), VCAM1.
MAP Kinase Pathway:  
COL1A1 (Collagen I), EGR1 (egr-1), FOS (c-fos), JUN (c-jun).
PI-3 Kinase / AKT Pathways:  
BCL2, CCND1 (cyclin D1), FN1 (fibronectin), HIF1A, JUN (c-jun), MMP7 (matrilysin), MYC (c-myc), TNFSF10 (TRAIL)
STAT Pathway:  
A2M (a2macroglobulin), BCL2, BCL2L1 (Bcl-XL), CSN2 (b –casein), CXCL9 (MIG), IL4, IL4R, IRF1, MMP10 (stromelysin-2), NOS2A (iNOS).
Stress / Heat Shock Pathways:  
HSF1 (tcf5), HSPA4 (hsp70), HSPB1 (hsp27), HSPB2, HSPCA (hsp90)
Stress / p38 & JNK Pathways:  
ABCB1 (Mdr1), ATF2, COL1A1 (Collagen I), DUSP1 (MKP1), ENPP2 (Autotaxin), FOS, HSPA4 (hsp70), HSPA5 (Grp78), HSPB1 (hsp27), HSPB2, MYC, TP53.
Survival / NFkB Pathway:  
AKT1, BCL2A1 (Bfl-1/A1), BCL2L1 (Bcl-xL), BIRC1 (NAIP), BIRC2 (c-IAP2), BIRC3 (c-IAP1), TNFAIP3 (A20), TRAF1.
TGFß Pathway:  
CDKN1A (p21Waf1, p21Cip1), CDKN1B (p27), CDKN1C (p57Kip2), CDKN2A (p16Ink4), CDKN2B (p15 Ink2b), CDKN2C (p18, cdk4 inhibitor), CDKN2D (p19).
Wnt Pathway:  
ABCB1 (Mdr1), BMP4, CCND1 (cyclin D1), ENPP2 (Autotaxin), FOSL1 (Fra-1), ID2, JUN (c-jun), MMP7, MYC (c-myc), VEGF, WISP1.

Apoptosis genes:
ABL1, BRCA1, CIDEA, CIDEB, GADD45A, GADD45G, GML, IHPK3, PCBP4, PDCD8, PPP1R15A, RAD21, TP53, TP73.
Cell cycle genes: Cell cycle arrest: CHEK1, CHEK2, DDIT3, GADD45A, GML, GTSE1, HUS1, MAP2K6, MAPK12, PCBP4, PPP1R15A, RAD17, RAD9A, SESN1, ZAK. Cell cycle checkpoint: ATR, BRCA1, FANCG, NBS1, RAD1, RBBP8, SMC1L1, TP53.
DNA repair:
Damaged DNA binding:
ANKRD17, BRCA1, DDB1, DDB2, DMC1, ERCC1, ERCC3, FANCG, FEN1, GTF2H3, MPG, MSH2, MSH3, MSH4, MSH5, MSH6, N4BP2, NBS1, OGG1, PMS2L4, PMS2L9, PNKP, RAD1, RAD18, RAD51, RAD51C, RAD51L1, RAD51L3, REV1L, SEMA4A, XPA, XPC, XRCC1, XRCC2, XRCC3.
Base-excision repair:
APEX1, MBD4, MPG, MUTYH, NTHL1, OGG1, RAD51L3, UNG, UNG2.
Double-strand break repair:
BRCA2, CIB1, FEN1, G22P1, KUB3, MRE11A, NBS1, PRKDC, RAD21, RAD50, RAD52, XRCC4, XRCC5.
Mismatch repair:
ABL1, ANKRD17, EXO1, MLH1, MLH3, MSH2, MSH3, MSH4, MSH5, MSH6, MUTYH, N4BP2, PMS1, PMS2, PMS2L4, PMS2L9, TP73, TREX1.
Others:
APEX2, ATM, ATRX, BTG2, CCNH, CDK7, CKN1, CRY1, CRY2, ERCC2, ERCC4, ERCC5, GTF2H1, GTF2H2, IGHMBP2, INPPL1, LIG1, LIG3, LIG4, MNAT1, NUDT1, PCNA, RAD23A, RAD23B, RAD54L, RPA1, RPA3, SUMO1, TREX2.

ATR/ATM signaling network:
53BP1, ATM, ATR, CDS1, CHEK1, CHEK2 (Rad53), FOXO3A, HUS1, MRE11A, NBS1 (nibrin), RAD1, RAD9, RAD17, RAD50, TREX1 (ATRIP);
DNA damage response pathways:
Cell cycle arrest pathway:
CDC20 (p55cdc), CDC25A, CDC25B, CDC25C, CDK4, CDKN1A (p21), CENPE, DDIT3 (GADD153), E2-EPF, EXT1, GADD45A, GADD45B, GADD45G, GTSE1 (B99), KNSL5 (MKLP-1), KNSL6 (MCAK), MDM2, PIN1, PPM1D (Wip1), PTPRCAP (LPAP), REPRIMO, SFN (14-3-3 sigma), TP53, WEE1;
Apoptosis pathway:
APAF1, BAK1, BAX, BBC3 (PUMA), BCL6, BIRC2 (MIHB), BIRC3 (MIHC), BNIP3 (NIP3), LGMN (Legumain), LRDD (PIDD), P53AIP1, TNF (TNF-a), TNFRSF4 (OX40), TNFRSF6 (Fas), TNFRSF10 (DR5);
Genome stability/repair pathway:
APEX (REF-1), ATRX (RAD54), BRCA1, BRCA2, BTG2, CKN1 (CSA), DDB1, DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, FEN1, GADD45A, GADD45B, GADD45G, H2AFL, MLH1, MPG, MSH2, MSH3, MSH6, PA26, PCNA, PMS1, PMS2, PRKDC (DNA-PK), PURA, RAD23A, RAD23B, RAD50, RAD51, RAD52, RPA3, RRM2B (p53R2), UNG, UNG2, XPA, XPC, XRCC1, XRCC2, XRCC3, XRCC4, XRCC5 (Ku-80)

DNA Damage Repair:
Base-excision repair:
APEX1, APEX2, FLJ10858, LIG3, MBD4, MPG, MUTYH, NEIL1, NEIL2, NTHL1, OGG1, PARP1, PARP3, SMUG1, TDG, UNG, UNG2, XRCC1.
Nucleotide Excision Repair:
ATXN3, BRIP1, CCNH, CDK7, CETN2, CKN1, DDB1, DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, GTF2H1, GTF2H2, GTF2H3, GTF2H4, LIG1, MMS19L, MNAT1, PNKP, POLL, RAD23A, RAD23B, RPA1, RPA3, SLK, XAB2, XPA, XPC. Mismatch Excision Repair:
ANKRD17, MLH1, MLH3, MSH2, MSH3, MSH4, MSH5, MSH6, N4BP2, PMS1, PMS2, PMS2L1, PMS2L9, POLD3, TP73, TREX1.
DSB Repair:
BRCA1, BRCA2, CIB1, DMC1, FEN1, G22P1, KUB3, LIG4, MRE11A, NBS1, PRKDC, RAD21, RAD50, RAD51, RAD51C, RAD51L1, RAD51L3, RAD52, RAD54B, RAD54L, XRCC2, XRCC3, XRCC4, XRCC5.
RAD6-dependent pathway:
RAD18, UBE2A, UBE2B, UBE2I, UBE2N, UBE2V2.
Other DNA-repair related genes:
ATM, ATR, EXO1, MGMT, TERF2, TERT.
Genome stability:
Telomere maintenance:
DKC1, MRE11A, PINX1, RAD50, RFC1, TEP1, TERF1, TERF2, TERF2IP, TERT, TINF2, TNKS, TNKS1BP1, TNKS2.
Other genome-stability related genes:
ATM, TOP3A, TOP3B.

Direct reversal of damage:
DEPC-1, MGMT  
Base exision repair:
ADPRT, ADPRTL2, ADPRTL3, APEX1 (APEX, REF1), APEX2 (APEXL2), FLJ10858, LIG3, MBD4, MUTYH (MYH), NEIL1, NEIL2, NTHL1 (NTH1), OGG1, SMUG1, TDG, UNG, XRCC1.
Nucleotide excision repair:
CCNH, CDK7, CETN2, CKN1 (CSA), DDB1, DDB2, ERCC1, ERCC2 (XPD), ERCC3 (XPB), ERCC4 (XPF), ERCC5 (XPG), ERCC6 (CSB), GTF2H1, GTF2H2, GTF2H3, GTF2H4, LIG1, MNAT1, RAD23A (HHR23A), RAD23B (HR23B), RPA1, RPA2, RPA3, XAB2 (HCNP), XPA, XPC.
Mismatch excision repair:
MLH1, MLH3, MSH2, MSH3, MSH4, MSH5, MSH6, PMS1, PMS2, PMS2L3, PMS2L4 (PMS6).
DSB repair-homologous recombination and end joining):
BRCA1, BRCA2 (FANCB/FANCD1), DCLRE1C (SNM1C), DMC1, G22P1 (KU70), LIG4, MRE11A, NBS1, PRKDC, RAD50, RAD51C, RAD51L1 (RAD51B), RAD51L3 (RAD51D), RAD54B, RAD54L, XRCC2, XRCC3, XRCC4, XRCC5 (KU80).
RAD6-dependent pathway:
RAD18, UBE2A (RAD6A), UBE2B (RAD6B), UBE2I (UBC9), UBE2N (UBC13), UBE2V2 (MMS2).
Other genome stability related genes: ATM, ATR, DCLRE1A (SNM1), DCLRE1B, DUT, EXO1, FEN1, PNKP, RECQL4, RECQL5, TERF1, TERF2, TERT (TCS1), TOP3A, TOP3B.

Apoptosis genes:
Induction of apoptosis:
BAK1, BAX, BID, CDKN1A, CRADD, DAPK1, EI24, FADD, FOXO3A, PCBP4, PLAGL1, PRKCA, PYCARD, TNFRSF10B, TNFSF6, TP53, TP73, TP73L.
Anti-apoptosis:
AATF, BAG1, BCL2, BCL2A1, BIRC5, BNIP3, CASP2, HDAC1, IGF1R, MCL1, NFKB1, RELA, SNCA, TNF.
Other apoptosis genes:
APAF1, BRCA1, CASP9, DAXX, E2F1, FAF1, GADD45A, GML, LRDD, P53AIP1, PPP1R13B, RAI, SIAH1, SIRT1, TP53BP2, TRAF2, TRAF4, TRAF5.
Cell cycle genes:
Cell cycle arrest:
CDKN1A, CDKN2A, CHEK1, CHEK2, GADD45A, GAS1, GML, GTSE1, MYC, PCAF, PCBP4, PLAGL1, PPP1R9B, RPRM, SESN1, SESN2, SESN3.
Cell cycle checkpoint:
ATR, BRCA1, CCNE2, CCNG2, CDKN2A, RB1, TP53.
Negative regulation of cell cycle:
ATM, BAX, BRCA1, CDKN2A, MSH2, NF1, PTEN, PYCARD, RB1, SMARCB1, TP53, TP73, TP73L, TSC1, TSC2, WT1.
Regulation of cell cycle:
BRCA2, CDC2, CDC25A, CDK4, CDK7, E2F1, E2F3, FRAP1, GAK, HK2, IGF1R, KRAS2, PLK1, PPM1D, PRKCA, SFN, STAT1, TADA3L, TP53BP2.
Other cell cycle genes:
BIRC5, CCNH, ESR1.
Cell growth, proliferation and differentiation genes:
Negative regulation of cell proliferation:
BAI1, BAP1, BCL2, BTG2, CDKN1A, CDKN2A, CHEK1, GAS1, GML, IFNB1, IL6, MDM2, MDM4, NF1, PCAF, PMP22, PPM1D, SESN1.
Positive regulation of cell proliferation:
CIAO1, IGF1R, IL6, SHC1, TSHR.
Cell proliferation:
BRCA1, CDC25A, CDC25C, CDK4, CDK7, CYR61, E2F1, MYC, PLK1, PPP1R9B, PRKCA, SCGB3A1, SFN.
Cell growth and differentiation:
COPEB, CYR61, ESR1, MCL1, MYOD1, NDRG1, PPP1R9B, PRKCQ, SCGB3A1, SHC1. Others:
FOXO3A, JUN, KRAS2, PHB, PML, PTTG1, TSC2.
DNA repair genes:
ATM, ATR, BRCA1, BTG2, CCNH, CDK7, FRAP1, GADD45A, MSH2, PTTG1, TP53.

P53 family:
TP53, TP63, TP73;
p53 upstream signal/p53 modifiers:
p53 expression and stability:
BZRP (pBR), CREBBP (CBP), D5S346 (DP1), E2F1 (E2F), EP300 (p300), MDM2, MTBP, NFKB1, NUMB;
p53 modification:
ATM, ATR, CCNH (cyclin H), CDK7 (CAK), CHEK1 (Chk1), CHEK2 (Chk2), CREBBP (CBP), CSNK1A1 (CK1), CSNK2A1, CSNK2A2, CSNK2B, EP300 (p300), HIPK2, KIP2, KIP3, MAP2K4, MAP2K7, MAPK8IP2, PCAF, PML, PRKCA, PRKCB1, PRKCG, PRKCQ, PRKDC (DNA-PK), SIRT1;
p53 interactions:
APEX (Ref-1), BAP1, BRAP, BRCA1, CDKN2A (p14ARF), E1B-AP5 (E1B55K), E2F1, MDM2, MYC, RASA1 (Ras), RB1 (pRB), TEAD1 (SV40), WRN, WT1;
p53 downstream signal/p53 effectors:
Cell-cycle control:
ABCB1 (MDR1), ACTA1 (actin), AD022, APR-3, CDC2, CDKN1A (P21Waf1), DAXX, ESR1, FADD, FAF1, GADD45A, GTSE1 (B99), HIF1A, HSPA4 (Hsp70), LRDD, MAP4, NDRG (RTP), PIG8 (E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP, THRA, TNFAIP1, TNFSF6, TP53TGI, TRAF1, TRAF4, TRAF5, WIG1;
Apoptosis regulators:
APAF1, BAX, BBC3 (PUMA), BCL2, CASP9 (Caspase-9), CTSD (Cathepsin D), LRDD (PIDD), P53AIP1, PMAIP1 (NOXA), PMP22 (GAS-3), TNF, TNFRSF10B (Killer5/DR5), TNFSF6 (Fas), TP53BP2 (ASPP2);
DNA repair:
GADD45A, RRM2B (p53R2);
Controllers of angiogenesis and metastasis:
BAI1, SERPINB5 (Maspin), THBS1 (TSP1)

Oxidative or Metabolic Stress:
CAT (catalase), CRYAB (a-Crystallin B), CYP1A1, CYP1B1, CYP2E1, CYP7A1, CYP7B1, EPHX2, FMO1, FMO5, GPX1 (glutathione peroxidase), GSR (glutathione reductase), GSTM3 (glutathione S-transferase M3), HMOX1, HMOX2, MT2A, POR, PRDX1, PRDX2, PTGS1, PTGS2 (cox-2), SOD1, SOD2.
Heat Shock:
DNAJA1, DNAJB4, HSF1 (tcf5), HSPA1A (hsp70 1A), HSPA1L (hsp70 1L), HSPA2 (hsp70 2), HSPA4 (hsp70), HSPA5 (grp78), HSPA6 (hsp70B), HSPA8, HSPA9B (mortalin-2), HSPB1 (hsp27), HSPCA (hsp90), HSPCB (hsp90 b), HSPD1 (chaperonin), HSPE1 (chaperonin 10), HSPH1 (hsp105).
Proliferation and Carcinogenesis:
CCNC (cyclin C), CCND1 (cyclin D1), CCNG1 (cyclin G), E2F1, EGR1, PCNA.
Growth Arrest and Senescence:
CDKN1A (p21Waf1/p21Cip1), DDIT3 (GADD153/CHOP), GADD45A, GADD45B, GDF15 (PLAB), IGFBP6, MDM2, TP53.
Inflammation:
CCL3 (MIP-1a), CCL4 (MIP-1b), CCL21 (MIP-2), CXCL10 (IP10), CSF2 (GM-CSF), IL1A, IL1B, IL6, IL18, LTA (TNF b), MIF, NFKB1, NOS2A (iNOS), SERPINE1 (PAI-1).
Necrosis or Apoptosis:
DNA Damage and Repair:
ATM, CHEK2 (RAD53), DDB1, ERCC1, ERCC3, ERCC4, ERCC5, RAD23A, RAD50, UGT1A10, UNG, XRCC1, XRCC2, XRCC4, XRCC5.
Apoptosis Signaling:
ANXA5 (annexin v), BAX, BCL2L1 (bcl-x), BCL2L2 (bcl-w), CASP1 (caspase1/ ICE), CASP8 (caspase8 / FLICE), CASP10 (caspase-10/mch4), NFKBIA (ikBa/mad3), TNF, TNFRSF1A (TNFR1), TNFSF6 (Fas Ligand), TNFSF10 (TRAIL), TRADD.

Antioxidant & Pro-Oxidant Enzymes:
ACADSB, CAT, GPX1, GPX2, SOD1, SOD2, XDH.
Molecular Chaperones:
Heat shock proteins: CRYAA, CRYAB, DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB11, DNAJB2, DNAJB4, DNAJB5, DNAJB6, DNAJB9, DNAJC4, DNAJC5, DNAJC6, DNAJC7, DNAJC8, DNAJC9, DNAJD1, HMOX1, HMOX2, HSPA12A, HSPA2, HSPA4, HSPA5, HSPA6, HSPA8, HSPA9B (GRP75), HSPB1, HSPB2, HSPB3, HSPCA, HSPCB, HSPD1, HSPE1, HSPH1, SERPINH1 (HSP47), TRA1 (GRP94).
Others:
BAG1, CALR, CANX, CCT2, CCT3, CCT4, CCT5, CCT7, CCT8, CLU, GRP58, HOP, PPID, ST13, TCP1.
Xenobiotic Metabolism:
Cytochrome P450s:
CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C9, CYP2D6, CYP2E1, CYP2F1, CYP4A11, CYP4B1, CYP7A1, CYP11A1, CYP11B2.
Others:
CES1, DIA1, EPHX2, FMO1, FMO4, FMO5, GSR, GSTM3, GSTO1 (GSTTLp28), GSTP1, GSTT1, MAOA, MAOB, MGST1, NAT2, NNMT, NUDT1, PON3, TPMT, UGT1A10.
Other Stress Proteins:
HSF1, HYOU1

Antioxidant & Pro-Oxidant Enzymes:
Acadsb, Cat, Gpx1, Gpx2, Sod1, Sod2, Sod3, Xdh.
Molecular Chaperones:
Heat shock proteins:
Cryaa, Cryab, Dnaja1, Dnaja2, Dnaja3, Dnaja4, Dnajb1, Dnajb10, Dnajb11, Dnajb12, Dnajb4, Dnajb5, Dnajb6, Dnajb9, Dnajc1, Dnajc4, Dnajc5, Dnajc6, Dnajc7, Dnajc8, Dnajc9, Dnajd1, Hmox1, Hmox2, Hsp105, Hspa1a, Hspa1l, Hspa12a, Hspa2, Hspa4, Hspa5, Hspa8, Hspa9a, Hspb1, Hspb2, Hspb3, Hspca, Hspd1, Hspe1, Serpinh1 (HSP47), Tra1 (GRP94).
Others:
Bag1, Cai (Erp72), Calr, Canx, Cct2, Cct3, Cct4, Cct5, Cct7, Cct8, Clu, Grp58, Hod, Ppid, St13, Tcp1, Tebp-pending (p23).
Xenobiotic Metabolism:
Cytochrome P450s:
Cyp11a1, Cyp11b2, Cyp17a1, Cyp1a1, Cyp1a2, Cyp1b1, Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c40, Cyp2d22, Cyp2e1, Cyp2f2, Cyp4a10, Cyp4b1, Cyp7a1, Cyp7b1.
Others:
Ces1, Dia1, Ephx2, Fmo1, Fmo4, Fmo5, Gsr, Gsta1, Gstm3, Gsto1 (GSTTLp28), Gstp1, Gstt1, Maoa, Maob, Mgst1, Nat2, Nnmt, Nudt1, Pon1, Pon2, Pon3, Sult1a1, Tpmt, Ugt1a6. Other Stress Proteins:
Hsf1, Hyou1, Stip1, Ubc.

Epidermal Growth Factor (EGF) Family:
AREG (Amphiregulin), DTR (HB-EGF), EGF, LOC145957 (Neuregulin 4), NRG1, NRG2, NRG3.
Fibroblast Growth Factor (FGF) Family:
FGF1, FGF2, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGF10, FGF11, FGF12, FGF13, FGF14, FGF16, FGF17, FGF18, FGF19, FGF20, FGF21, FGF23. Platelet-Derived Growth Factor (PDGF) Family:
FIGF (VEGFD), PDGFA, PDGFB, PDGFC, SCDGF-B (PDGFD), VEGF, VEGFB, VEGFC. Tumor Growth Factor (TGF) Family:
TGFA, TGFB1, TGFB2, TGFB3.
Neuronal Growth Factors:
BDGF, CNTF, GDNF, KLK2 (NGFA), MDK (Midkine), NGFB, NRP1 (Neuropilin 1), NRP2, NT6G, NTF3, NTF5.
Cytokines:
CSF1 (M-CSF), CSF2 (GM-CSF), CSF3 (G-CSF), EPO, IL1A, IL1B, IL2, IL3, IL4, IL5, IL6, IL7, IL8, IL9, IL10, IL11, IL12A, IL12B, IL13, IL14, IL15, IL16, IL17, IL17B, IL17C, IL17E, IL17F, IL18, IL19, IL20, IL22, KITLG (SCF), LTA (TNF beta), TNF.
Other Related Growth Factor Genes:
CTGF, CXCL1 (MGSA), ECGF1 (PD-ECGF), GH1, GH2, HGF, IGF1, IGF2, INS, PGF (PLGF), PTN.

Drug Resistance:
ABCB1 (PGY1, MDR1), ABCC1 (MRP1), ABCC2 (cMOAT, MRP2), ABCC3 (MOAT-D, MRP3), ABCC5 (MRP5), ABCC6 (MRP6, CFTR), ABCG2 (BCRP), BAX, BCL2, BCL2L1 (bcl-x), MVP (LRP), RB1, TOP1, TOP2A, TOP2B, TP53 (p53); Drug Metabolism: ARNT, BLMH, COMT, CRABP1, CRR9 (DKFZP761M2324), CYP1A1, CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E, CYP3A4, CYP3A5, DHFR, EPHX1, EPHX2, GSK3A, GSTM1, GSTP1, MRP1-ESTs, NAT2, NQO1 (DIA4), SOD1, STE, TPMT, TYMS (TS), UGCG;
DNA Repair:
APC, ATM, BRCA1, BRCA2, ERCC3, MGMT, MLH1, MSH2, XPA, XPC; Cell Cycle: CCND1 (cyclin D1), CCNE1 (cyclin E1), CDK2, CDK4, CDKN1A (p21Waf1, p21Cip1), CDKN1B (p27Kip1), CDKN2A (p16Ink4), CDKN2D (p19Ink4d);
Growth Factor Receptors:
EGFR (ERBB1), ERBB2 (Her-2), ERBB3, ERBB4, FGF2, IGF1R, IGF2R, MET; Hormone Receptors:
AR, ESR1 (ER-alpha), ESR2 (ER-beta-cx), PPARA, PPARD, PPARG, PPARGC1, RARA, RARB, RARG, RXRA, RXRB, RXRG, SRD5A2;
Transcription Factors:
AHR, AP1S1, ELK1, FOS (c-fos), HIF1A, MAFB, MYC (c-myc), NFKB1, NFKB2, NFKBIB (TRIP9), NFKBIE, RELB (l-rel), TNFRSF11A (Rank)

Androgen receptor and associated proteins:
AR, NCOA4 (ARA70), NSD1 (ARA267b), PAK6, RAN (ARA24), RNF14 (ARA54), TGFB1I 1 (ARA55), TMF1 (ARA160);
Androgen-responsive prostate cancer-related genes:
Androgen receptor & associated proteins:
NCOA4 (ARA70), PAK6, TMF1 (ARA160);
Proteases and Enzymes:
ACPP, ADH1B, AKR1B1 (aldose reductase), ALDH1A1 (ALDH1), ARSDR1, CYP2C18, DHCR24 (seladin-1), FOLH1 (PSMA), GPX5, HBOA, KLK2, KLK3 (PSA), KLK4, PPAP2A, SRD5A2, TGM4 (hTGP), TMPRSS2;
Transcriptional factors/DNA-binding proteins:
CALR, CHD4, FGF8, HMG20B, NDRG1 (Drg1), NKX3A (NKX3.1), NR1D1 (ear-1), PART1, PDEF, SHBG, SREBF1, SREBF2, TRIM28 (KAP1/TIF1beta);
Genomic maintenance and cell cycle regulation:
BCRP1 (BAF), CSNK2B, IMPDH2, ODC1, PCNA, PIG8, RPA3, XRCC2; Androgen-independent prostate cancer-related genes:
ANXA7, APOE, CDH1, GAGEB1 (PAGE-1), GSTP1, HPN (Hepsin), LIM, OR51E2 (PSGR), PCA3 (DD3), PSCA, PTEN, SPARCL1 (HEVIN), STEAP, TNFRSF6 (FAS); Genes switched from androgen responsive to androgen independent in recurrent prostate cancer after hormone therapy:
ADAM9, ADM, LDHA, MDH1, ODC1, PCNA, TUBA3;
PI3K/AKT/FRAP pathway related genes that were associated with hormone-refractory cell growth:
CCND1, CDS1, EIF4EBP1, FKBP5, FKBP8, FOXJ1, MAPKAPK2, NFKBIA, ODC1; Genes associated with invasive prostate cancers:
C20orf1 (FLS353), C7, FAT, FBXL11, GAGEC1, IGF1, KCNMB1, MTA1, MYBL2, PPAP2B, RAB5A, RAP1A, SFRP4;
Other Related Genes:
AIG-1, ANKH, AS3, CDC37, CLU (Clusterin), CSTB, DBI, DKFZP434D146 (SGEF), FKBP5 (AIG6), JTB (PAR), TMEPAI (PMEPA1)

Genes directly associated with breast cancer:
AZGP1 (zinc-a-glycoprotein), BPAG1 (plectin), CDKN1A (p21Wap1/Cip1), CLDN7 (claudin-7), CLU (clusterin), ERBB2 (Her-2), FGF1, FLRT1 (fibronectin), GABRP (GABAa), GNAS1, ID2, ITGA6 (6 integrin), ITGB4 ( 4 integrin), KLF5 (GC Box BP), KRT19 (Keratin 19), KRTHB6 (hair-specific type II keratin), MACMARCKS, MT3 (metallothionectin-III), MUC1 (mucin), PTGS2 (COX-2), RAC2 (p21Rac2), S100A2, SCGB1D2 (lipophilin B), SCGB2A1 (mammaglobin 2), SCGB2A2 (mammaglobin 1), SPRR1B (Spr1), THBS1, THBS2, THBS4, TNFAIP2 (B94);
Genes associated with the estrogen receptor signaling pathway:
AR, C3 (Complement component 3), CCND1, CTSD (cathepsin D), ESR1, ESR2, GATA3, HSP28, KRT18, KRT19 (Keratin 19), PGR, SERPINA3 (a1-antichmotrypsin), SLC7A5, STC2, TFF1 (pS2), TFF3;
Genes associated with breast cancer prognosis:
BAD, BAG1, BCL2, CCNA1, CCNA2, CCND1, CCNE1, CCNE2, CDH1 (E-cadherin), CDKN1B (p27Kip1), CDKN2A (p16INK4a), COL6A1, CTNNB1 (b-catenin), CTSB (cathepsin B), EGFR, ERBB2 (Her-2), ESR1, ESR2, F3 (TF), FOSL1 (FRA-1), GATA3, GSN (Gelsolin), IGFBP2, IL2RA, IL6, IL6R, IL6ST (glycoprotein 130), ITGA6 (6 integrin), JUN, KLK5, KRT19, MAP2K7 (c-Jun), MKI67 (Ki-67), NGFB (NGF), NGFR, NME1 (NM23A), PGR, PLAU (uPA), PTEN, SERPINB5 (maspin), SERPINE1 (PAI-1), TGFA, THBS1 (thrombospondin-1), TIE (Tie-1), TNFRSF6 (Fas), TNFSF6 (FasL), TOP2A (topoisomerase Iia), TP53, VEGF;
Genes associated with response to chemotherapy:
BCL2, BCL2L2, CD44, COX17, CTSD (cathepsin D), CYP19, DLC1, ESR1, ESR2, HMGB1, KIT, NFYB, PAPPA, PGR, PPP1R15A (GADD34), RPL27, VEGF

Potential Diagnosis Markers: Cell cycle:
Cell cycle arrest/checkpoint:
MYC, RB1, TP53.
Negative regulation of cell cycle:
ATM, BAX, BRCA1, EGFR, ESR1, NME1, PTEN, RB1, TP53.
Regulation of cell cycle:
BCL2, BRCA2, CCND1, CCNE1, CDK4, FGF3, FGF8, IGF2, MAPK3, PCNA, PRKCA, TGFA, TGFB1, TGFB2, TGFB3, VEGF.
DNA replication:
CDK2, EGF, IGF1, PCNA.
Cell growth & proliferation:
Growth factors/cytokines:
BMP6, CSF1, CSF3, EGF, FGF18, FGF3, FGF8, IGF1, IGF2, TGFA, TGFB1, TGFB2, TGFB3, TNF, VEGF.
Positive regulation of cell proliferation:
CDK2, CSF1, CSF3, EGF, FGF18, FGF3, IGF1, VEGF.
Negative regulation of cell proliferation:
BCL2, NME1, ODZ1, PLG.
Regulation of cell growth:
ESR2, IGFBP3, TP53, TSG101.
Other genes involved in cell growth & proliferation:
AR, BRCA1, CDK4, EGFR, ERBB2, ERBB4, ESR1, MYC, PCNA, PRKD1, PRL.
Cell differentiation:
CSF1, IGFBP3, TP53.
Apoptosis:
Induction of apoptosis:
BAX, MX1, PRKCA, PRKCE, TP53.
Anti-apoptosis:
AKT1, BAG3, BCL2, BCL2L1, PRKCZ, TGFB1, TNF.
Other apoptosis genes:
BRCA1, IGFBP3, VEGF.
DNA repair:
ATM, BRCA1, BRCA2, PCNA, RAD51, TP53, XRCC3.
Angiogenesis factors:
FGF3, VEGF.
Cell adhesion molecules:
CD34, CDH1, CTNNB1, ITGB3, PECAM1.
Extracellular matrix (ECM) molecules:
ALB, BRCA1, BRCA2, COL4A2, CSF3, CTSD, EGF, ERBB2, FGF18, FGF3, FGF8, IGF1, IGF2, IGFBP3, INS, KLK13, MMP11, MMP9, ODZ1, PRL, SERPINE1, SHBG, TGFA, VEGF.
Protein kinases:
IGFBP3, PTEN.
Protein phosphatases:
IGFBP3, PTEN.
Transcription factors and regulators:
AR, BRCA1, BRCA2, CTNNB1, EGR3, ESR1, ESR2, FOS, JUN, MYC, NR4A1, PCNA, PGR, RB1, SP1, TNF, TP53, TSG101.
Proteases/protease inhibitors:
CTSB, CTSC, CTSD, CTSE, CTSL2, KLK13, MMP11, MMP9, PCSK6, PLG, SERPINE1. Other potential diagnostic markers:
ABCB1, ABCG2, AKAP1, CEACAM5, CYB5, CYC1, CYP19A1, GSTM1, GSTM3, KRT18, KRT19, MIB1, MUC1, MUC19, PALM2-AKAP2, VIM.
Potential Prognosis Markers:
Cell cycle:
Cell cycle arrest/checkpoint:
CCNE2.
Negative regulation of cell cycle:
ESR1, EXT1.
Regulation of cell cycle:
BCL2, CCNB1, CCNB2, CDC25B, CENPF, MKI67, MYBL2, PCTK1, PSMD2, TGFB3, VEGF.
DNA replication:
MCM6, ORC6L, RFC4, RRM2.
Other cell cycle genes:
BIRC5, BUB1, CKS2, MAD2L1, SMC4L1, STK6.
Cell growth & proliferation:
Growth factors/cytokines: ESM1, FGF18, TGFB3, VEGF.
Positive regulation of cell proliferation:
CDC25B, FGF18, FLT1, VEGF.
Negative regulation of cell proliferation:
BCL2, BTG2.  
Regulation of cell growth:
CHPT1, ESM1, IGFBP5, WISP1.
Other genes involved in cell growth & proliferation:
BUB1, CKS2, ESR1, MAPRE2, MKI67.
Cell differentiation:
NDRG1.
Apoptosis:
Anti-apoptosis:
BAG1, BCL2, BIRC5, BNIP3, MYBL2.
Other apoptosis genes:
RAD21, STK3, VEGF.
DNA repair:
BTG2, RAD21.
Angiogenesis factors:
FLT1, VEGF.
Cell adhesion molecules:
WISP1
Extracellular matrix (ECM) molecules:
ADM, COL4A2, CP, ESM1, FGF18, FLT1, IGFBP5, MATN3, MMP11, MMP9, RBP3, TFRC, VEGF, WISP1.
Protein kinases:
BUB1, CCNE2, CDC42BPA, CKS2, FLT1, MELK, PCTK1, STK3, STK32B, STK6. Protein phosphatases:
CDC25B, MTMR2.
Transcription factors and regulators:
BTG2, ESR1, EZH2, HMGB3, IVNS1ABP, KIAA1442, MCM6, MLLT10, MYBL2, PGR, PIR, SEC14L2, TBX3, TRIP13.
Proteases/protease inhibitors:
BIRC5, CTSL2, GGH, MMP11, MMP9, PCSK6, PITRM1, RBP3, TFRC, UCHL5.
Other potential prognostic markers:
ACADS, ALDH4A1, ALDH6A1, AP2B1, ASNS, ASPM, BBC3, BM039, C20orf103, C20orf28, C20orf46, CA9, CD68, CENPA, CIRBP, CTPS, DCK, DEGS, DEPDC1, DKFZP434B168, DKFZp762E1312, DLG7, ECT2, EGLN1, EIF2C2, ERP70, EVL, FBP1, FBXO31, FBXO5, FGD6, FLJ10134, FLJ10156, FLJ10511, FLJ10901, FLJ12150, FLJ21924, FLJ22341, FUT8, GBE1, GCN1L1, GMPS, GNAZ, GPR126, GPSM2, GRB7, GSTM1, GSTM3, HRASLS, HRB, IHPK2, ITR, KIAA0882, KIAA1181, KIAA1217, KIAA1324, KIAA1683, KIF14, KIF21A, KIF3B, KNTC2, KRT18, LCHN, LGP2, LOC388134, LOC56901, LYRIC, M160, MCCC1, MGAT4A, MIR, MLF1IP, MRPL13, MS4A7, MYRIP, NMB, NMU, NUSAP1, ODZ3, OXCT, PALM2-AKAP2, PAQR3, PECI, PEX12, PFKP, PGK1, PIB5PA, PLEKHA1, PRAME, PRC1, PRO2000, PSMD7, PTDSS1, PTPLB, QDPR, RAB27B, RAB6B, RAI2, RAMP, RASL11B, RPS4X, RRAGD, SACS, SCUBE2, SERF1A, SLC2A3, SLC7A1, Spc25, ST7, STMN1, STX1A, SYNCRIP, TK1, TMEFF1.

Androgen receptor and associated proteins:
AR, NR1I3, RNF14, SHBG, SRD5A2, TGFB1I1.
Apoptosis:
Induction of apoptosis:
BAK1, BAX, CASP3, CDKN1A, DAPK1, INHA, MAPK1, NOX5, PRKCA, PRKCE, TIMP3, TNFSF10, TP53.
Caspases:
CASP1, CASP3, CASP7.
Anti-apoptosis:
AKT1, BCL2, BCL2L1, IGF1R, IL1A, IL2, NFKB1, PRKCZ, TGFB1, TNF.
Other apoptosis genes:
AGTR2, BRCA1, CLU, E2F1, IGFBP3, IL1B, IL24, NFKBIA, PAWR, VEGF.
Cell cycle:
Cell cycle checkpoint:
BRCA1, CDKN2A, RB1, TP53.
Cell cycle arrest:
CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN3, INHA, MAPK12, MYC, RASSF1, TP53.
Negative regulation of cell cycle:
APC, BAX, BRCA1, CDKN1C, CDKN2A, CDKN2B, EGFR, ESR1, FHIT, INHA, KLK10, MAPK12, MTSS1, PTEN, RASSF1, RB1, TP53.
Other regulators of cell cycle:
BCL2, CCND1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, E2F1, FGF1, FGF10, FGF2, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, HK2, HRAS, IGF1R, IGF2, IL1A, IL1B, MAPK1, MAPK13, MAPK3, MAPK4, MAPK6, MAPK7, PCNA, PRKCA, TGFA, TGFB1, TGFB2, TGFB3, VEGF.
Cell growth/proliferation:
Cytokines:
BMP6, IL12A, IL1A, IL1B, IL2, IL24, INHA, TNF, TNFSF10.
Growth factors:
BMP6, EGF, FGF1, FGF10, FGF11, FGF12, FGF13, FGF14, FGF16, FGF17, FGF18, FGF19, FGF2, FGF20, FGF21, FGF22, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, GRP, IGF1, IGF2, IL12A, IL1A, IL1B, IL2, INHA, TGFA, TGFB1, TGFB2, TGFB3, VEGF.
Positive regulation of cell proliferation:
CDK2, EGF, FGF10, FGF18, FGF2, FGF4, FGF7, IGF1, IGF1R, IL2, VEGF.
Negative regulation of cell proliferation:
BCL2, CD164, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C, CDKN3, GNRH1, IGFBP6, IL1A, IL1B, ODZ1, PAWR, PLG, TGFB1I1.
Other regulators of cell growth and proliferation:
AR, BRCA1, CDK3, CDK4, CDK5, CDK6, CDK7, CDK9, E2F1, EGFR, ENO1, ERBB2, ESR1, ESR2, IGFBP3, IGFBP6, IL2, INSL4, MYC, NOX5, NR6A1, PAP, PCNA, PRKCQ, PRKD1, PRL, TP53.
Cell differentiation:
FGF22, FGF23, FGF9, IGFBP3, IL2, INHA, KLK6, TP53.
Hormones and related genes:
Hormones:
CHGB, GNRH1, IGF1, IGF2, INHA, INSL3, INSL4, PRL.
Hormone regulators:
KLK6, SHBG.
Thyroid hormone receptors:
NR1D1, NR1H3, NR1I3, NR2F6, NR4A3.
Other steroid hormone receptors:
AR, ESR1, ESR2, NR0B1, NR0B2, NR1D2, NR1H2, NR1H4, NR1I2, NR2C1, NR2C2, NR2E1, NR2E3, NR2F1, NR2F2, NR3C1, NR3C2, NR4A1, NR4A2, NR5A1, NR5A2, NR6A1, PGR, RARB.
Angiogenesis factors:
FGF1, FGF2, FGF6, KLK3, KRT1, VEGF.
Extracellular matrix (ECM):
APOC1, BRCA1, CHGA, CHGB, CLU, COL1A1, COL6A1, EGF, ERBB2, ERK8, FGF1, FGF10, FGF11, FGF13, FGF14, FGF16, FGF17, FGF18, FGF2, FGF20, FGF21, FGF22, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, GNRH1, IGF1, IGF2, IGFBP3, IGFBP6, IL12A, IL1A, IL1B, IL2, IL24, INHA, INSL3, INSL4, KLK10, KLK12, KLK13, KLK14, KLK15, KLK3, KLK4, KLK5, KLK6, KLK9, MMP2, MMP9, MSMB, NTN4, ODZ1, PAP, PLAU, PRL, PSAP, SERPINA3, SHBG, TGFA, TIMP3, VEGF.
Cell adhesion:
Cell-cell adhesion:
CD44, CDH1, CDH10, CDH19, CDH20, CDH7, CDH9.
Homophilic cell adhesion:
CDH1, CDH10, CDH13, CDH18, CDH19, CDH20, CDH7, CDH8, CDH9, ROBO2. Cell-matrix adhesion:
CD44, ILK, ITGA1.
Other cell adhesion regulators:
APC, CD164, COL6A1, MTSS1, PAP, TGFB1I1, TNF.
Proteases and inhibitors:
Kallikreins:
KLK1, KLK10, KLK11, KLK12, KLK13, KLK14, KLK15, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9.
Metallopeptidases:
FOLH1, MMP2, MMP9.
Other proteases:
CASP1, CASP3, CASP7, PLAU, PLG.
Protease inhibitors:
SERPINA3, TIMP3.
Protein kinases and inhibitors:
Cyclin-dependent protein kinases:
CDK2, CDK3, CDK4, CDK5, CDK7, CDK9, CDK Inhibitors, AGTR2, CDKN1A, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CDKN2C.
JUN kinases:
MAPK10, MAPK8, MAPK9.
MAP kinases:
ERK8, MAPK1, MAPK10, MAPK11, MAPK12, MAPK13, MAPK14, MAPK3, MAPK4, MAPK6, MAPK7, MAPK8, MAPK9.
MAP kinase kinases:
MAPK10, MAPK14.
Protein kinase C members:
PRKCA, PRKCB1, PRKCE, PRKCG, PRKCH, PRKD3.
Janus kinases:
INSL3, TYK2.
Other protein kinases:
AKT1, CDK6, CDK8, DAPK1, EGFR, ERBB2, HK2, HK3, IGF1R, ILK, MAP2K4, MAP3K1, PRKCD, PRKCI, PRKCQ, PRKCZ, PRKD1, PRKD2, RNASEL, SRC, TGFA. Transcription factors and regulators:
Nuclear Receptors:
ESR1, ESR2, NR0B1, NR0B2, NR1D1, NR1D2, NR1H2, NR1H3, NR1H4, NR1I2, NR1I3, NR2C1, NR2C2, NR2E1, NR2E3, NR2F1, NR2F2, NR2F6, NR3C1, NR3C2, NR4A1, NR4A2, NR4A3, NR5A1, NR5A2, NR6A1, PGR, RARB.
Other transcription factors and regulators:
AR, BRCA1, CDK7, CDK8, CDK9, E2F1, EGR3, ELL, ENO1, EZH1, EZH2, FGF10, HIF1A, JUN, MYC, NCOA4, NFKB1, NFKBIA, NKX3-1, PAWR, PIAS1, RB1, RNF14, SOX2, TGFB1I1, TNF, TP53, TRPS1.
Genes involved in stress response:
Antibacterial humoral response:
IL12A, IL1B, MAPK11, MAPK14, NFKB1, NR4A2.
Inflammatory response:
IL1A, IL1B, NFKB1, NR3C1, PAP, SERPINA3, TNF.
Other stress response genes:
AKT1, BRCA1, CD164, FGF10, FGF16, FGF7, HIF1A, IL2, IL24, INHA, KLK6, KRT1, MAPK1, MAPK11, MAPK13, MAPK14, MAPK8, MAPK9, NFKB1, NFKBIA, ODZ1, TNF, TNFSF10, TP53, VEGF.
Other prostate cancer markers:
AGR2, AIG1, AKAP1, AKAP2, CANT1, CAV1, CDH12, CLDN3, CLN3, CYB5, CYC1, DAB2IP, DES, DNCL1, ELAC2, ENO2, ENO3, FASN, FLJ12584, FLJ25530, GAGEB1, GAGEC1, GGT1, GSTP1, HIP1, HUMCYT2A, IL29, K6HF, KAI1, KRT2A, MIB1, PART1, PATE, PCA3, PIAS2, PIK3CG, PPID, PR1, PSCA, SLC2A2, SLC33A1, SLC43A1, STEAP, STEAP2, TPM1, TPM2, TRPC6.



Drug Transporters:
Metallothioneins:
MT1A, MT1E (hMT-Ie), MT1G, MT1H, MT1L, MT2A, MT3, MT1X.
P-Glycoprotein family:
ABCB1 (PGY1, mdr-1), ABCB4 (mdr-3), ABCC1, ABCC2, ABCC3, ABCC5 (MRP5), ABCG2.
Phase I Metabolizing Enzymes:
P450 gene family:
CYP11A, CYP1A1, CYP1B1, CYP2A6, CYP2B, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E, CYP2F1, CYP3A4, CYP3A5, CYP3A7, CYP4A11, CYP4B1, CYP4F3, CYP7A1, CYP7B1, CYP8B1, CYP24, CYP-M (LOC57404), P450RAI-2, POR, TBXAS1.
Phase II Metabolizing Enzymes:
Acetyltransferases:
ACAT1, ACAT2, CHAT, CRAT, DLAT, HAT1, HBOA, MORF, NAT1, NAT5 (LOC51126). Epoxide Hydrolases:
EPHX1, EPHX2, LABH1, LTA4H (leukotriene A4 hydrolase).
Glutathione S-Transferases:
GSTA2, GSTA3, GSTA4, GSTM2, GSTM3, GSTM5, GSTP1, GSTT1, GSTT2, MGST1, MGST2, MGST3.
Methyltransferases:
COMT, HNMT, NNMT, TPMT.
Sulfotransferases:
CHST1, CHST2, CHST3, CHST4, CHST5, CHST6, CHST7, CHST8, CST, HNK-1ST, STE, SULT1A1, SULT1A2, SUPT1B1, SULT1C1, SULT1C2, SULT2A1, SUL2B1, SULT4A1, TPST1, TPST2.
UDP Glycosyltransferases:
UGT1A1, UGT2A1, UGT2B, UGT2B10, UGT2B4.

Apoptosis genes:
Induction of apoptosis:
BAX, CASP10, CDKN1A, IL18, LTA, TNFSF10, TNFSF6, TP53, TRADD.
Anti-apoptosis:
AKT1, BAG1, BCL2, BCL2L1, BCL2L2, IGF1R, IL1A, NFKB1, TNF.
Other genes involved in apoptosis:
AHR, BRCA1, CASP1, CASP8, CLU, DNAJA3, E2F1, GADD45A, GADD45B, IL1B, NFKBIA, TNFRSF1A.
Cell cycle genes:
Cell cycle arrest and checkpoint:
BRCA1, CDKN1A, CDKN1B, CDKN2A, CDKN2D, DDIT3, GADD45A, MYC, RB1, TP53. Negative regulation of cell cycle:
APC, ATM, BAX, BRCA1, CDKN2A, CDKN2D, MLH1, MSH2, RB1, TP53.
Other cell cycle genes:
ABL1, AHR, BCL2, BRCA2, CCNC, CCND1, CCNE1, CCNG1, CCT2, CCT4, CCT7, CDK2, CDK4, CHEK2, DNAJA2, E2F1, FGF2, IGF1R, IL1A, IL1B, PCNA, RB1.
Cell growth, proliferation and differentiation genes:
Chemokines and cytokines:
CCL21, CCL3, CCL4, CSF2, CXCL10, GDF15, IL18, IL1A, IL1B, IL6, LTA, MIF, TNF, TNFSF10, TNFSF6.
Growth factors and recepters:
EGFR, ERBB2, ERBB3, ERBB4, FGF2, IGF1R, IGF2R, MET.
Genes negatively regulating cell growth and proliferation:
BCL2, CDKN1A, CDKN1B, CDKN2A, CDKN2D, ESR2, IGFBP6, IL1A, IL1B, IL6, MDM2, MT3.
Genes positively regulating cell growth and proliferation:
CDK2, CXCL10, DNAJA2, FGF2, IGF1R, IL18, IL6, NOS2A, TNFRSF11A.
Other genes regulating cell growth and proliferation:
ABL1, AR, BCR, BRCA1, CCND1, CDK4, DDIT3, E2F1, ESR1, FOS, IGFBP6, MYC, NFKB2, PCNA, PRDX1, RARA, RARB, TOP1.
Transporters:
ABCB1, ABCB4, ABCC1, ABCC2, ABCC3, ABCC5, ABCC6, ABCG2, AP1S1, AR, CRABP1, IGF2R, RAD50, TPMT.
Response to stress:
Response to drug:
ABCB1, ABCB4, ABCC1, ABCC6, ABCG2, CTPS, MVP, NAT8.
Response to DNA damage stimulus:
ATM, BRCA1, CHEK2, DDIT3, GADD45A, RAD23A, XRCC2.
Response to oxidative stress:
CAT, GPX1, GPX2, NUDT1, PRDX2, SOD1, SOD2.
Response to other stresses:
AHR, AKT1, CCL4, CES1, DNAJB4, DNAJB5, EPHX1, EPHX2, ERCC1, GADD45B, GSR, GSTA3, GSTA4, GSTT1, HIF1A, HSPB2, HYOU1, MT1X, MT3, NFKB1, NFKBIA, NQO1, PON3, PPARG, PPARGC1A, RAD51, SERPINH1, TNF, TRA1.
Chaperones/heat shock proteins:
BAG1, CALR, CANX, CCT2, CCT3, CCT4, CCT5, CCT7, CCT8, CRYAA, CRYAB, DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB11, DNAJB2, DNAJB4, DNAJB5, DNAJB9, DNAJC4, DNAJC5, DNAJC7, DNAJC8, HSF1, HSPA1A, HSPA1L, HSPA2, HSPA4, HSPA6, HSPA8, HSPA9B, HSPB1, HSPB2, HSPB3, HSPCA, HSPCB, HSPD1, HSPE1, HSPH1, HYOU1, SERPINH1, ST13, TCP1, TRA1.
Transcription factors and regulators:
Ligand-dependent nuclear receptors:
AHR, ESR1, ESR2, NR1I2, NR1I3, PPARD, PPARG, PPARGC1A, RARA, RARB, RARG, RXRA, RXRB, RXRG.
Others:
ABL1, AR, ARNT, BRCA1, BRCA2, CALR, CCNC, DDIT3, E2F1, EGR1, ELK1, ERCC3, FOS, HIF1A, HOP, HSF1, MYC, MYST2, MYST4, NFKB1, NFKB2, NFKBIA, NFKBIB, RB1, RELB, SAFB, TNF, TP53.
Drug metabolizing enzymes:
Acyltransferases:
ACAT1, CHAT, CRAT, DLAT, HAT1, NAT1, NAT2, NAT5.
Methyltransferases:
COMT, HNMT, MGMT, NNMT, TPMT, TYMS.
Sulfotransferases:
CHST1, CHST10, CHST2, CHST3, CHST4, CHST5, CHST6, CHST7, CHST8, GAL3ST1, SULT1A1, SULT1B1, SULT1C1, SULT1C2, SULT1E1, SULT2A1, SULT2B1, SULT4A1, TPST1, TPST2.
Oxidoreductases:
ACADSB, CAT, CYP11A1, CYP11B2, CYP1A1, CYP1A2, CYP1B1, CYP20A1, CYP24A1, CYP26B1, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP2F1, CYP3A4, CYP3A5, CYP4A11, CYP4B1, CYP4F3, CYP7A1, CYP7B1, CYP8B1, DHFR, DIA1, DPYD, FMO1, FMO4, FMO5, GPX1, GPX2, GSR, HMOX1, HMOX2, MAOA, MAOB, NOS2A, NQO1, POR, PRDX1, PRDX2, PTGS1, PTGS2, SOD1, SOD2, SRD5A2, TBXAS1, XDH
Glutathione peroxidases:
GPX1, GPX2, GSTA3, GSTA4, GSTM1, GSTM2, GSTM3, GSTM5, GSTO1, GSTP1, GSTT1, GSTT2, MGST1, MGST2, MGST3.

Permissibility and vessel tone:
Angiotensin system:
ACE, ACE2, AGT, AGTR1 (AT1), AGTR2 (AT2), ENPEP (aminopeptidase A); NO system: NOS2A (iNOS), NOS3 (eNOS);
Prostacyclin system:
ALOX5 (5-lipoxygenases), PLA2G4C, PTGIS, PTGS2 (COX-2);
Endothelin system:
EDN1 (ET-1), EDN2 (ET-2), EDN3 (ET-3), EDNRA (ETA), EDNRB (ETB);
Superoxide anions system:
PTGS2, SOD1, XDH;
Angiogenesis:
Adhesion molecule:
CDH5, ITGA5, ITGAV, ITGB3, PECAM1;
Growth factors and receptors:
ANGPT1, ANGPT2, FGF2, FLT1 (VEGFR1), FLT4 (VEGFR3), KDR (VEGFR2), TEK, VEGF; ECM: MMP1, MMP2, MMP9, MMP14 (MT1-MMP), TIMP1;
Growth inhibitor:
CHGA (vasostatin), COL18A1 (endostatin), PLG (angiostatin), THBS1 (thrombospondin-1);
Endothelial cell activation:
Adhesion molecules expression:
CDH5, ICAM1, ICAM2, ICAM3, ITGA5, ITGAV, ITGB1, ITGB3, OCLN (Occludin), PECAM1 (CD31); SELE (E-Selectin), SELL (L-Selectin), SELPLG (P-Selectin), VCAM1; Change phenotype from antithrombotic to prothrombotic:
ANXA5 (annexin V), CPB2 (TAFI), F3 (tissue factor), PLAT (tPA), PLAU (u-PA); SERPINE1 (PAI), TFPI, TFPI2, THBD (thrombomodulin), VWF;
Cytokine production:
CCL2 (MCP-1), CCL5 (RANTES), CCL20 (exodus-1), CSF2 (GM-CSF), CSF3 (G-CSF), CX3CL1, IFNB1, IL1B; IL3, IL6, IL7, IL8, IL11, IL14, IL15, TNF;
Endothelial cell injure (apoptosis):
Pro-apoptosis:
ADAM17 (TNFcE), BAX, CASP1, CASP3, CASP6, CASP10, CRADD, MMP9, RIPK1, TNFRSF6 (Fas), TNFSF6 (FasL); TNFSF10 (Trail);
Anti-apoptosis:
BCL2, BCL2A1, BCL2L1 (Bcl-xl), CFLAR (c-FLIP), FN1, PTGS2, TIMP1, TNFAIP3 (A20), TNFRSF10C, TNFRSF10D, TNFRSF11B (OPG)

Growth factor and associated molecule:
BMP1, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMP8, BMPR1A, CASR, CSF2 (GM-CSF), CSF3 (G-CSF), EGF, EGFR, FGF1, FGF2, FGF3, FGFR1, FGFR2, FGFR3, FLT1, GDF10, IGF1, IGF1R, IGF2, MADH1, MADH2, MADH3, MADH4, MADH5, MADH6, MADH7, MADH9, MSX1, MSX2, NFKB1, PDGFA, RUNX2 (CBFA1), SOX9, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, TNF (TNFa), TWIST, VDR, VEGF, VEGFB, VEGFC; Matrix and its associated protein:
ALPL, ANXA5, ARSE, BGLAP (osteocalcin), BGN, CD36, CD36L1, CD36L2, COL1A1, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL7A1, COL9A2, COL10A1, COL11A1, COL12A1, COL14A1, COL15A1, COL16A1, COL17A1, COL18A1, COL19A1, CTSK, DCN, FN1, MMP2, MMP8, MMP9, MMP10, MMP13, SERPINH1 (CBP1), SERPINH2 (CBP2), SPARC, SPP1 (osteopontin);
Cell adhesion molecule:
ICAM1, ITGA1, ITGA2, ITGA3, ITGAM, ITGAV, ITGB1, VCAM1

Molecular Markers for Stem and Differentiated Cells:
ABCG2, ACTA2, ACTC, ACTG2, AFP, CD24, CD34, CD44, CD9, CDH15, CER1, CNP, COL6A2, EGFR, EGR2, FABP4, FABP6, FABP7, FGF2, FGF4, FGFR4, FLJ21195 (Prdc-pending), FZD9, GATA2, GATA4, GCG, GCM2, GFAP, GJA7, GJB1, GJB3, GJB4, GJB5, IL6ST, INA, ISL1, KDR, KRT14, KRT15, KRT17, KRT8, LIF, LIFR, MAP1B, MAP2, MYH11, MYH6, MYL4, NCAM1, NCAM2, NEFL, NES, NGFR, NKX2-5, NKX2B, NPPA, NTF3, NUMB, OLIG1, OLIG2, PAX6, PDGFRA, PLP1, POU3F2, POU3F3, POU5F1, POU6F1, PROML1, PROX1, PTPRC, S100B, SIAT8A, SLC1A2, SLC1A6, SLC2A1, SNAI1, SNAI2, SOX1, SOX10, SOX2, SYT1, THY1, TUBB4, UTF1, VIM, ZFP42. Growth factors and Cytokines:
ACVR1, ACVR2, ACVRL1, BDNF, BMP1, BMP10, BMP15, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMP8, BMPR1A, BMPR1B, BMPR2, CNTF, CNTFR, DLK1, EGF, FGF1, FGF10, FGF11, FGF12, FGF14, FGF16, FGF17, FGF18, FGF19, FGF20, FGF21, FGF23, FGF3, FGF5, FGF6, FGF7, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FLJ10314 (Nodal), FZD1, FZD2, FZD3, FZD4, FZD7, FZD8, GDF1, GDF11, GDF2, GDF3, GDF5, GDF8, GDF9, IGF1, IGF1R, IGF2, IGF2R, IL6, IL6R, INHBA, INHBB, INS, INSRR, ITGB7, LOC145957 (Neuregulin 4), NEUROG1, NGFB, NOTCH1, NRG1, NRG2, NTRK2, PDGFA, PDGFB, PDGFRB, PTCH, PTCH2, TGFB1, TGFB2, TGFB3, TGFBR1, TGFBR2, TGFBR3, VEGF, WNT11, WNT2, WNT3, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A.
ECM Molecules:
CDH1, CDH2, CDH3, CDH4, CDH5, CST3, CTNNA1, CTNNA2, CTNNAL1, CTNNB1, CTNND2, ICAM1, ICAM5, ITGA2, ITGA2B, ITGA3, ITGA4, ITGA5, ITGA6, ITGA7, ITGA8, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB2, ITGB3, ITGB4, ITGB5, ITGB6, NTRK3, PECAM1, TNC, VCAM1.
Others:
ACTB, C3orf4, CCNE1, CCNE2, CCNG2, CDK4, CDKN1A, CDKN1B, CDKN2A, CDKN2D, CXCL12, CXCR4, DNMT1, DNMT2, DNMT3A, DNMT3B, DNMT3L, ESG1, FOXG1A, FOXH1, FOXM1, FOXO1A, GAPD, HSPA9B, MDM2, NOG, PPIA, PTEN, PUM1, PUM2, RB1, RBL1, RBL2, RPL13A, SHH, SOX13, SOX15, SOX17, SOX18, SOX3, SOX4, SOX5, SOX6, TEP1, TERF1, TERT, TINF2, TP53

Cell Surface/Lineage Markers:
CCR1, CD164, CD1D, CD2, CD34, CD3D, CD3G, CD4, CD44, CD80, CD86, CD8A, CSF1, DLL1, FLT3LG, FUT10, FZD1, GALNAC4S-6ST, IL31RA, IL6ST, JAG1, JAG2, KDR, KIT, KITLG, LRMP, MAL, NOTCH2, NOTCH4, PECAM1, PTPRC, SFXN1, STIM2, TEK, TLR3, TLR4, TNFRSF7, TNFSF11.
Cytokines and Growth Factors:
Cytokines:
CSF1, CSF2, FLT3LG, IL10, IL11, IL12B, IL17E, IL1A, IL2, IL20, IL4, IL7, INHA, INHBA, PF4, SPP1, THPO, TNFSF11.
Growth factors:
CSF1, CSF2, IL10, IL11, IL1A, IL2, IL4, IL7, INHA, INHBA, JAG1, JAG2, KITLG, SPP1, THPO, VEGF.
Cell Cycle Regulators:
Cell cycle arrest:
CDKN1B, INHA, INHBA, MYC, NOTCH2.
Other cell cycle regulators:
APC, GFI1, HDAC4, HDAC5, HDAC7A, HDAC9, IL1A, JAG2, SCAND1, STAT1, VEGF. Blood Cell Activation:
B-cell activation:
HDAC4, HDAC5, HDAC7A, HDAC9, IL4. T-cell activation: CD2, CD3D, CD3G, CD80, CD86, CD8A, IRF4.
Genes activating other blood cell types:
CD2, IL11, IL12B, IL2, IL31RA, PF4, TLR4.
Cell Differentiation:
B-cell differentiation:
AICDA, BLNK, GALNAC4S-6ST, HDAC4, HDAC5, HDAC7A, HDAC9, IL10, IL11, IL4, INHA, INHBA, KLF6, TNFRSF7.
T-cell differentiation:
CD2, CD4, CD80, CD86, IL12B, IL2, IL27, IRF4, JAG2, NOS2A, RHOH, SOCS5, TNFRSF7, WWP1.
Differentiation regulators for other blood cell types:
ANGPT1, BGLAP, CD3G, CSF1, DLL1, IFI16, IL11, IL20, IL31RA, INHA, INHBA, JAG1, MAL, MAP4K1, MLF1, NCOA6, NOTCH1, NOTCH2, NOTCH4, PAX5, PF4, RASGRP4, SCAND1, SPP1, TAL1, TLR3, TLR4, TNFSF11.
Hematopoiesis Regulators:
ASH2L, BCL11A, CD164, CSF1, DLL1, ERAF, FEZ2, FUT10, IFI16, IL10, IL20, IL31RA, JAG1, LMO2, MLF1, MMP9, NOTCH2, NOTCH4, STIM2, TRIM10, ZNF160.
Signaling Molecules:
Notch signaling pathway:
DLL1, JAG1, JAG2, NOTCH2, NOTCH4.
Wnt receptor signaling pathway:
APC, FZD1, LEF1, WNT3A.
JAK-STAT cascade:
IL31RA, SOCS5, STAT1, STAT3, STAT4.
Cell surface receptors linked to signal transduction:
CCR1, CD14, CD2, CD3D, CD3G, CD4, CSF2, FZD1, IL6ST, INHA, INHBA, PRL, PTPRC, TNFRSF7.
Transcription Factors and Regulators:
ASH2L, BCL11A, CBFB, CD80, CD86, CEBPE, CEBPG, EGR1, ETS1, ETV6, GATA1, GATA2, GFI1, HDAC4, HDAC5, HDAC7A, HDAC9, HOXB4, IFI16, IL31RA, IRF4, IRF8, KLF6, LEF1, MAFB, MYC, NCOA6, NFYA, NOTCH1, NOTCH2, NOTCH4, PAX5, RBPSUH, RHOH, RUNX1, SCAND1, STAT1, STAT3, STAT4, TAL1, VAV1, WWP1, ZNF160.

Cytokines:
CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), FGF2, IFNA1, IFNB1, IFNG, IL1A, IL1B, IL2, IL3, IL4, IL5, IL6, IL7, IL8, IL9, IL10, IL11, IL12A, IL12B, IL13, IL14, IL15, IL16, IL17, IL18, IL19, KITLG, PDGFB, TNF.
Cytokine Receptors:
IL2RA, IL4R, IL5RA, IL8RA, IL8RB, IL12RB1, IL12RB2, IL13RA1, IL13RA2, IL18R1. Chemokines:
CCL1, CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, CCL13, CCL17, CCL18, CCL19, CCL20, CCL22, CCL24,CX3CL1, CXCL1, CXCL2, CXCL3, XCL1.
Chemokine Receptors:
CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CX3CR1, GPR2, XCR1.
Th2 Cytokine Signaling Pathway:
FOS, GATA3, JAK1, JAK3, STAT6, TBX21, TGFB1, TNFSF6, YY1.
IgE Receptor:
CYSLTR1, FCER1A, FCER2, LTB4R, LTB4R2, LTBR

Response to Stress:
Inflammatory response:
CCL11, CCL2, CCL20, CCL5, CCR1, CCR2, IL1R1, IL1R2, IL8, ITGB2, NFKB1, NOS3, PTGS2, SELE, SPP1, TNF, TNFRSF5.
Response to oxidative stress:
APOE, CCL5, SOD1, SOD2.
Response to pest, pathogen or parasite:
CCL2, CCL20, CCR2, CSF2, CSF3, FN1, IL13, IL1B, IL4, IL6, IL7, ITGB2, TNF, TNFRSF5.
Response to virus:
CCL11, CCL5, IFNAR2, TNF.
Response to wounding:
CCR1, CCR2, CTGF, FN1, PDGFB, TNF, VWF. Other stress response genes: APOA2, IFNG, PPARG, VEGF.
Apoptosis:
Anti-apoptosis:
BCL2, BCL2A1, BCL2L1, BIRC3, CCL2, CFLAR, IL1A, IL2, NFKB1, SERPINB2, SPP1, TGFB1, TNF, TNFAIP3, TNFRSF6.
Induction of apoptosis:
APOE, BAX, BID, CFLAR, TNFRSF6.
Other apoptosis genes:
IL1B, IL5, ITGB2, TNFRSF5.
Blood Coagulation and Circulation:
Blood coagulation:
CD36, F7, FGA, FGB, ITGA2, ITGB3, LPA, SERPINE1.
Circulation:
APOA1, APOA4, APOB, APOE, COL3A1, DSCR1, ELN, ENG, LPA, LPL, NPY, OLR1. Platelet activation:
PDGFA, PDGFB, PDGFRB, TNFRSF5, VWF.
Regulation of blood pressure:
ACE, FGA, FGB.
Adhesion Molecules:
Cell-cell adhesion:
CD44, CDH5, ICAM1, ICAM2, ITGB2, SELE, SELL, TNF, VCAM1, VEGF.
Cell-matrix adhesion:
CD44, ITGA2, ITGA5, ITGAX, ITGB2, ITGB3, ITGB5, ITGB7, SPP1.
Other genes involved in adhension:
CCL11, CCL2, CCL5, CCR1, CD36, CTGF, ELN, ENG, FN1, IL8, LAMA1, SCARB1, SELPLG, THBS4, TNC, VWF.
Extracellular Molecules (ECMs):
ECM proteas inhibitors:
LPA, SERPINB2, SERPINE1.
ECM proteases:
ACE, MMP1, MMP3, MMP9.
Extracellular matrix structural constituent:
COL3A1, ELN, FN1.
Other extracellular molecules:
ADFP, APOA1, APOA2, APOA4, APOB, APOE, CCL11, CCL2, CCL20, CCL5, CSF2, CSF3, CTGF, DTR, F7, FGA, FGB, FGF2, IFNAR2, IFNG, IL13, IL1A, IL1B, IL2, IL3, IL4, IL5, IL6, IL7, IL8, LAMA1, LCAT, LIF, LPL, NPY, PDGFA, PDGFB, PLTP, SPP1, THBS4, TNC, VEGF, VWF.
Lipid Transport and Metabolism:
Cholesterol metabolism:
ABCA1, APOA1, APOB, APOE, CETP, IL4, LCAT, LDLR.
Fatty acid metabolism:
CD36, FABP3, LPL, PPARA, PTGS1, PTGS2. Lipid transport: ABCA1, APOA1, APOA2, APOA4, APOB, APOE, CETP, FABP3, LDLR, LPA, LPL, MSR1, PLTP.
Lipoprotein metabolism: APOA1, APOA2, APOA4, APOE, LDLR, LPL. Steroid metabolism: NR1H3, PPARA, PPARD, PPARG, RXRA. Other lipid metabolism: ADFP, APOA2, APOA4, APOE, LPA, PLTP.
Cell Growth and Proliferation:
Growth factors and receptors:
CSF2, KDR, PDGFRB, SPP1.
Negative regulation of cell proliferation:
BCL2, FABP3, IL1A, IL1B, IL6, IL8.
Positive regulation of cell proliferation:
CSF1, CSF3, DTR, FGA, FGB, FGF2, IL2, IL3, IL5, IL6, IL7, LIF, VEGF.
Regulation of cell cycle:
DUSP6, FGF2, IL1A, IL1B, PDGFA, PDGFB, TGFB1, TGFB2, TGFB3, VEGF.
Other genes involved in cell growth and proliferation:
CTGF, ELN, IFNG, IL13, IL4, NPY, TNFRSF5.
Transcription Regulators:
Nuclear receptor:
NR1H3, PPARA, PPARD, PPARG, RXRA. Other transcription regulaters: DSCR1, EGR1, IL8, KLF2, NFKB1, SOD2, TNF, TNFAIP3.

Adaptor Proteins:
FADD, IRAK1, IRAK2, MYD88, NCK2, TNFAIP3, TRADD, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6.
Cell Surface Receptors:
ACVR1, ACVR1B, ACVR2, ACVR2B, ACVRL1, CD28, CD3E, CD3G, CD3Z, CD69, CD80, CD86, CNR1, CTLA4, CYSLTR1, FCER1A, FCER2, FCGR3A, GPR44, HAVCR2, OPRD1, P2RX7, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10. Chemokine & Receptors:
BLR1, CCL1, CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL15, CCL16, CCL17, CCL18, CCL19, CCL20, CCL21, CCL22, CCL23, CCL24, CCL25, CCR1, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CCR9, CX3CL1, CX3CR1, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL10, CXCL11, CXCL12, CXCL13, CXCR4, GPR2, SCYE1, SDF2, XCL1, XCL2, XCR1.
Cytokine & Receptors:
AMH, AMHR2, BMPR1A, BMPR1B, BMPR2, C19orf10 (IL27w), CER1, CSF1, CSF2, CSF3, DKFZp451J0118, FGF2, GFI1, IFNA1, IFNB1, IFNG, IGF1, IL1A, IL1B, IL1R1, IL1R2, IL2, IL2RA, IL2RB, IL2RG, IL3, IL4, IL4R, IL5, IL5RA, IL6, IL6R, IL6ST, IL7, IL8, IL8RA, IL8RB, IL9, IL9R, IL10, IL10RA, IL10RB, IL11, IL11RA, IL12A, IL12B, IL12RB1, IL12RB2, IL13, IL13RA1, IL13RA2, IL15, IL15RA, IL16, IL17, IL17R, IL18, IL18R1, IL19, IL20, KITLG, LEP, LTA, LTB, LTB4R, LTB4R2, LTBR, MIF, NPPB, PDGFB, TBX21, TDGF1, TGFA, TGFB1, TGFB1I1, TGFB2, TGFB3, TGFBI, TGFBR1, TGFBR2, TGFBR3, TH1L, TNF, TNFRSF1A, TNFRSF1B, TNFRSF7, TNFRSF8, TNFRSF9, TNFRSF11A, TNFRSF21, TNFSF4, TNFSF5, TNFSF6, TNFSF11, VEGF, ZFPM2, RNF110 (ZNF144). Signal Transduction Proteins:
CABIN1, CALM1, CALM2, CALM3, CAMK2B, CAMK4, CDC25A, CDKN1A, CDKN2B, CHUK, CSNK2A1, CSNK2B, ENG, EVI1, GSK3A, GSK3B, IKBKB, IKBKE, IKBKG, IL18BP, ITK, JAK1, JAK2, JAK3, KPNA5, KPNB3, LAG3, LAT, MADH1, MADH2, MADH3, MADH4, MADH5, MADH6, MADH7, MADH9, MAP2K4, MAP2K7, MAP3K1, MAP3K2, MAP3K7, MAP3K7IP1, MAP3K14, MAPK3, MAPK8, MAPK9, MAPK10, MAPK14, MHC2TA, NAP4, NBL1, NMA, NUP214, PAK1, PLAU, PPP3CB, PPP3CC, PPP3R1, PTPRC, RIPK1, SERPINE1, SLA, SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS7, TBK1, TIMP1, TRPV6, TSC22, TYK2, VAV1, VAV2, VAV3, XPO5.
Responsive Genes and Other Related Genes:
AGT, BAD, BCL2, BCL3, BF, C3, CHRD, CKTSF1B1, COL1A1, COL1A2, COL3A1, FST, HRAS, ICAM1, ICAM2, ICAM3, ICAM4, ICAM5, IGFBP3, IGSF6, ITGB5, ITGB7, IVL, MGC27165, MYF5, NCAM1, NOS2A, ORM1, PIN1, RFX1, RFX2, RFX3, RFX4, RFX5, RFXANK, RFXAP, RFXDC1, SAA1, SELE, SELL, SELPLG, SFN, TGIF, VCAM1. Transcription Factors:
ATF2, CEBPB, CREB1, CREBBP, EGR1, EGR2, EGR3, ELK1, ELK3, EP300, FKBP1B, FLJ14639 (NIP45), FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1, ICOS, IRF1, JUN, JUNB, JUND, MAF, MAX, MEF2A, MEF2B, MEF2D, MYC, NFAT5, NFATC1, NFATC2, NFATC3, NFATC4, NFKB1, NFKB2, NFKBIA, NFKBIB, NFKBIE, NFKBIL1, NFKBIL2, NFRKB, RAF1, REL, RELA, RELB, RUNX1, RUNX2, SP1, SP3, SRF, STAT1, STAT4, STAT6, TFCP2, YY1.

Biomarkers for Risk of Cardiovascular Disease:
Adhesion-Related Proteins:
ICAM1, ITGA1, ITGA2, ITGA2B, ITGA3, ITGA4, ITGA5, ITGA6, ITGA7, ITGA8, ITGA9, ITGA10, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB2, ITGB3, ITGB4, ITGB5, ITGB6, ITGB7, ITGB8, PECAM1, SELE (E-Selectin), SELL (L-Selectin), SELP (P-Selectin), SELPLG, VCAM1.
Inflammation-Related Proteins:
CCL2 (MCP-1), CCR2, IFNG, IL1B, IL1RN, IL6, IL8, IL10, IL18, LTA, NFKB1. Apoptosis-Related Proteins:
TNF, TNFRSF1A (TNF-RI), TNFRSF1B (TNF-RII), TNFRSF5 (CD40), TNFRSF6 (Fas), TNFSF5 (CD40 ligand), TNFSF6 (FasL).
Extracellular Transporters & Carrier Proteins:
APOA1, APOA2, APOA4, APOA5, APOB, APOC1, APOC2, APOC3, APOD, APOE, APOF, APOH, LPA (Lipoprotein A).
Others:
EDN1 (ET-1), EDN2 (ET-2), EDN3 (ET-3), FGA (Fibrinogen alpha), FGB (Fibrinogen beta), FGG (Fibrinogen gamma), HMOX1 (Heme oxygenase-1), MMP1, MMP2, MMP9, MRPL15, NOS2A, OLR1 (oxLDL), PAPPA, PLA2G7 (Lp-PLA2), PLAT (tPA), PLAU (uPA), PLAUR (uPAR), PPARG, SAA1, SERPINE1 (PAI-1), THBD (thrombomodulin), TIMP1, VWF.
Genes Associated with Failing or Infracted Heart:
CKM (CK-MB), CRP, CTF1 (cardiotrophin-1), F3 (Tissue factor), IL6ST (GP130), MB (Myoglobin), NPPA (ANP), NPPB (BNP), TNNC1 (Troponin-C), TNNI3 (Troponin-I), TNNT2 (Troponin-T)

Molecules regulating inflammatory response:
CCL2 (MCP-1), CCL5 (Rantes), CCL11 (eotaxin), CCL20 (MIP-3 alpha), CCR1, CCR2, CSF1 (M-CSF), CSF2 (GM-CSF), CSF3 (G-CSF), DSCR1, IFNAR2, IFNG, IL1A, IL1B, IL1R1, IL1R2, IL1RL1, IL2, IL3, IL4, IL5, IL6, IL7, IL8, IL13, LIF, NFKB1, NFKBIL2, TNF; Adhesion molecules and extracellular matrix molecules:
CD44, CDH5 (VE-cadherin), COL3A1 (collagen), FN1 (fibronectin), ICAM1, ICAM2, ITGA2, ITGA5, ITGAX, ITGB2 (LFA-1), ITGB3, ITGB5, ITGB7, LAMA1 (laminin), MMP1, MMP3, MMP9, SELE (E-selectin), SELL (L-selectin), SELPLG (P-selectin), SERPINB2 (PAI-2), SERPINE1 (PAI-1), SPP1, THBS4, TNC, VCAM1;
Cholesterol/lipid transport and metabolism:
ABCA1 (ABC-1), ADFP (adipophilin), CD36, MSR1 (SR-A), OLR1 (LOX-1), SCARB1 (SR BI);
Growth related molecules:
CTGF, DTR (HBEGF), EGR1, FABP3 (MDGI), FGF2, KDR (Flk-1), PDGFA, PDGFB, PDGFRB, TGFB1, TGFB2, TGFB3, VEGF;
Stress related molecules:
HSPBAP1 (HspB), KLF2 (LKLF), NOS3 (ecNOS), PTGS1 (Cox-1), PTGS2 (COX-2), SOD1, SOD2;
Nuclear Receptors:
NR1H3 (LXRA), PPARA, PPARD, PPARG, RXRA;
Apoptosis:
BAX, BCL2, BCL2A1, BCL2L1, BID, BIRC3, CFLAR (FLIP), DUSP6 (MKP3), EGR1, SERPINB2 (PAI-2), SERPINE1 (PAI-1), TNFAIP3 (A20), TNFRSF6 (Fas)

Receptors, Transporters & Channels:
ABCC8, ADRB3, AQP2, CD28, CEACAM1, CTLA4, GCGR, GLP1R, HLA-DQB1, HLA-DRB5, ICAM1, IL4R, INSR, NSF, RAB4A, SELL (LECAM-1), SLC2A4 (GLUT4), SNAP23, SNAP25, STX4A, STXBP1, STXBP2, STXBP4, TNFRSF1A, TNFRSF1B, VAMP3, VAPA, VAPB.
Nuclear Receptors:
PPARA, PPARG.
Metabolic Enzymes:
ACE, ACLY, ADPRT, ENPP1, FBP1, G6PC, G6PD, GCK, GPD1, GSK3B, HMOX1, IDE, ME1, NOS3, PCK1, PFKFB3, PRKAA1, PRKAG2, PYGL.
Secreted Factors:
AGT, CCL5 (Rantes), CCR2 (MCP-1), GCG, IFNG, IL6, IL10, IL12B, INS, RETN, TGFB1, TNF, VEGF.
Signal Transduction:
AKT2, C20orf97, DUSP4, IGFBP5, IKBKB (IKKbeta), INPPL1 (SHIP2), IRS1, IRS2, MAP2K3, MAP2K6, MAPK8 (JNK1), MAPK14 (p38 MAPK), PIK3C2B, PIK3CD, PIK3R1, PRKCB1, PTPN1 (PTP-1B).
Transcription Factors:
CEBPA, CEBPB, FOXC2, FOXG1B, FOXP3, HNF4A, IPF1 (PDX-1), NEUROD1, NFKB1, NRF1, PAX4, PPARGC1A, PPARGC1B, SREBF1, SREBF2, TCF2 (HNF1b), TITF1.

Receptors, Transporters & Channels:
Abcc8, Adra1a, Adrb3, Aqp2, Axl, Cd28, Ceacam1, Ctla4, Gcgr, Glp1r, H2-Ab1, H2-Eb1, Icam1, Il4ra, Insr, Lepr, Nsf, Rab4a, Sell (LECAM-1), Slc2a4 (GLUT4), Slc14a2, Snap23, Snap25, Stx4a, Stxbp1, Stxbp2, Stxbp