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A New Paradigm in DNA Sequencing: Highly Accurate Single-Molecule Long Reads

DNA测序的新范式:高度准确的单分子长序列

 

日期:2018年12月11日(星期二
时间:太平洋标准时间上午9点
美国东部时间下午12:00
下午五点,格林尼治时间

随着最近发布的Sequel System 6.0, PacBio通过向用户提供生成高精度单分子测序的能力,彻底改变了长读测序。
用户不再需要为了准确性而牺牲读取长度,因为现在可以同时读取15 kb的Sanger-quality。
 
新版本通过以下方式提高了单分子实时(SMRT)测序的性能和可承受性:

提供个人长读,准确率大于99%
将通量提高到每个SMRT单元50 Gb
根据插入大小,平均读取长度可达100,000 bp
听到乔纳斯Korlach博士,我们的首席科学官,和戴夫Corney博士,副首席科学家,下一代测序从GENEWIZ,当他们描述这个独特的技术和应用,如全基因组测序的好处,结构性变异检测,有针对性的测序和RNA序列完整的成绩单使用Iso-Seq方法。
 
从这些新SMRT测序有经验的用户,这个网络研讨会将提供一个更新最近的性能改进,科学发现由PacBio和未来的应用程序,以支持你的研究。
 
你会学到什么?

SMRT测序的优势
最新的续作系统跨应用的性能
用户现在通过高保真阅读实现了什么

A New Paradigm in DNA Sequencing: Highly Accurate Single-Molecule Long Reads

Date: Tuesday, December 11, 2018
Time: 9:00 a.m. PST
12:00 p.m. EST
5:00 p.m. GMT

With the recent release of Sequel System 6.0, PacBio has revolutionized long-read sequencing by providing users the ability to generate highly accurate single-molecule reads. Users no longer need to compromise read length for accuracy, because it is now possible to have both including Sanger-quality reads as long as 15 kb.

 
The new release improves the performance and affordability of Single Molecule, Real-Time (SMRT) Sequencing by:

  • Providing individual long reads with greater than 99% accuracy
  • Increasing the throughput up to 50 Gb per SMRT Cell
  • Delivering average read lengths up to 100,000 bp, depending on insert size

Hear from Jonas Korlach, Ph.D., our Chief Scientific Officer, and Dave Corney Ph.D., Associate Principal Scientist, Next Generation Sequencing from GENEWIZ, as they describe this unique technology and the benefits in applications such as whole genome sequencing, structural variant detection, targeted sequencing and RNA sequencing of full-length transcripts using the Iso-Seq method. 
 
From those new to SMRT Sequencing to experienced users, this webinar will provide an update on recent performance improvements, scientific discoveries powered by PacBio and future applications to enable your research.
 
What will you learn?

    • The advantages of SMRT Sequencing
    • The latest Sequel System performance across applications
    • What a user is now achieving with high-fidelity reads

posted on 2020-10-05 17:03  王闯wangchuang2017  阅读(135)  评论(0编辑  收藏  举报

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