ilifeiscience

[置顶] Improving gene annotation of peanut genome by integrated proteogenomics workflow（通过整合的蛋白质组学工作流程改善花生基因组的基因注释）解读人：卜繁宇

摘要：期刊名：J. Proteome Res. 发表时间：2020年5月 IF：3.86 单位：广东省农业科学院物种：花生技术：蛋白质基因组学一、概述：）本研究采用蛋白质基因组学策略，整合花生多个组织（种子、壳、雌蕊柄）的RNA-Seq和蛋白质组学数据，以改善花生的基因注释。最终，在蛋白水平上发阅读全文

posted @ 2020-09-11 11:02 ilifeiscience 阅读(234) 评论(0) 推荐(0) 编辑

[置顶] Characterization of urinary exosomes purified with size exclusion chromatography and ultracentrifugation（尺寸排阻色谱与超速离心纯化尿液外泌体的表征）解读人：徐宁

摘要：期刊名：Journal of proteome research 发表时间：2020年6月 IF：4.074 单位：复旦大学化学系和生物医学科学研究所大连医科大学附属第二医院泌尿外科技术：分子排阻色谱，超速离心，Western blot，纳米颗粒跟踪分析，荧光显微，Nano-LC-MS/MS等阅读全文

posted @ 2020-09-11 10:57 ilifeiscience 阅读(748) 评论(0) 推荐(0) 编辑

[置顶] Serum Targeted HILIC-MS Metabolomics-based Analysis in Infants with Ureteropelvic Junction Obstruction（血清靶向HILIC-MS代谢组学在婴幼儿肾盂输尿管连接部梗阻中的应用）解读人：黄旭蕾

摘要：期刊名：Journal of Proteome Research 发表时间：（2020年5月） IF：3.780 单位：1Paediatric Nephrology Unit, First Department of Paediatrics, Hippokratio Hospital, Aristo 阅读全文

posted @ 2020-09-11 10:53 ilifeiscience 阅读(182) 评论(0) 推荐(0) 编辑

[置顶] Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses（蛋白质组学揭示了人诱导的多能干细胞（iPSC）神经元中表达的突变Tau对外泌体的失调）解读人：梁玉婷

摘要：期刊名：MCP 发表时间：（2020年4月） IF：4.828 单位：Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego 物种：人技术：LC-MS/MS Tandem M 阅读全文

posted @ 2020-07-01 11:29 ilifeiscience 阅读(283) 评论(0) 推荐(0) 编辑

[置顶] Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction（解读人：王茹凯）

摘要：文献名：Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction（时空蛋白质组学揭示了下泌阅读全文

posted @ 2020-05-06 17:44 ilifeiscience 阅读(157) 评论(0) 推荐(0) 编辑

[置顶] Large-scale Identification of N-linked Intact Glycopeptides in Human Serum using HILIC Enrichment and Spectral Library Search （解读人：陈凌云）

摘要：文献名：Large-scale Identification of N-linked Intact Glycopeptides in Human Serum using HILIC Enrichment and Spectral Library Search （利用HILIC富集和谱图库搜索对人血清阅读全文

posted @ 2020-05-06 17:40 ilifeiscience 阅读(490) 评论(0) 推荐(0) 编辑

[置顶] Improving Identification of In-organello Protein-Protein Interactions Using an Affinity-enrichable, Isotopically Coded, and Mass Spectrometry cleavable Chemical Crosslinker （解读人：王欣然）

摘要：文献名：Improving Identification of In-organello Protein-Protein Interactions Using an Affinity-enrichable, Isotopically Coded, and Mass Spectrometry clea 阅读全文

posted @ 2020-05-06 17:33 ilifeiscience 阅读(218) 评论(0) 推荐(0) 编辑

[置顶] 文献名：Repeat-Preserving Decoy Database for False Discovery Rate Estimation in Peptide Identication （用于肽段鉴定中错误发生率估计的能体现重复性的诱饵数据库）

摘要：文献名：Repeat-Preserving Decoy Database for False Discovery Rate Estimation in Peptide Identication （用于肽段鉴定中错误发生率估计的能体现重复性的诱饵数据库）期刊名：Journal of Proteome 阅读全文

posted @ 2020-03-31 18:12 ilifeiscience 阅读(571) 评论(0) 推荐(0) 编辑

[置顶] Mol Cell Proteomics. |The Challenge of Classifying Metastatic Cell Properties by Molecular Profiling Exemplified with Cutaneous Melanoma Cells and Their Cerebral Metastasis from Patient|(解读人：徐宁)

摘要：文献名：The Challenge of Classifying Metastatic Cell Properties by Molecular Profiling Exemplified with Cutaneous Melanoma Cells and Their Cerebral Metast 阅读全文

posted @ 2020-03-29 15:44 ilifeiscience 阅读(240) 评论(0) 推荐(0) 编辑

[置顶] Mol Cell Proteomics. |Proteomic analysis reveals that Topoisomerase 2A is associated with defective sperm head morphology|(解读人：卜繁宇)

摘要：文献名：Proteomic analysis reveals that Topoisomerase 2A is associated with defective sperm head morphology 作者：Jacob Netherton1, Rachel A. Ogle1, Louise H 阅读全文

posted @ 2020-03-29 15:36 ilifeiscience 阅读(234) 评论(0) 推荐(0) 编辑

[置顶] Mol Cell Proteomics. |Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome|膀胱输尿管反流类复发性尿路感染患者的尿液蛋白质组学初步研究|(解读人：王聚)

摘要：文献名：膀胱输尿管反流类复发性尿路感染患者的尿液蛋白质组学初步研究期刊名：Molecular & Cellular Proteomics 发表时间：（2020年1月） IF：4.828 单位：波士顿儿童医院马萨诸塞大学医学院物种：人类尿液技术：非靶向蛋白质组学一、概述：尿路感染（UT 阅读全文

posted @ 2020-03-29 15:30 ilifeiscience 阅读(170) 评论(0) 推荐(0) 编辑

[置顶] Mol Cell Proteomics. | Discovery of Species-unique Peptide Biomarkers of Bacterial Pathogens by Tandem Mass Spectrometry-based Proteotyping|基于串联质谱的蛋白质分型技术发现细菌病原体特有的多肽生物标志物|(解读人：黄旭蕾)

摘要：（基于串联质谱的蛋白质分型技术发现细菌病原体特有的多肽生物标志物）期刊名：Molecular & Cellular Proteomics 发表时间：（2020年3月） IF：4.828 单位：Department of Infectious Diseases, Institute of Biome 阅读全文

posted @ 2020-03-29 15:26 ilifeiscience 阅读(325) 评论(0) 推荐(0) 编辑

[置顶] Lipid Profiling of Serum and Lipoprotein Fractions in Response to Pitavastatin Using an Animal Model of Familial Hypercholesterolemia（使用家族性高胆固醇血症动物模型检测匹伐他汀对血清和脂蛋白组分脂质谱的影响）

摘要：文献名：Lipid Profiling of Serum and Lipoprotein Fractions in Response to Pitavastatin Using an Animal Model of Familial Hypercholesterolemia（使用家族性高胆固醇血症动阅读全文

posted @ 2020-03-27 11:31 ilifeiscience 阅读(265) 评论(0) 推荐(0) 编辑

[置顶] Alterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effects（大脑的定量蛋白质组学揭示了薯蓣皂苷元对脑缺血再灌注效应的分子机制）

摘要：文献名：Alterations of brain quantitative proteomics profiling revealed the molecular mechanisms of diosgenin against cerebral ischemia reperfusion effect 阅读全文

posted @ 2020-03-25 19:14 ilifeiscience 阅读(249) 评论(0) 推荐(0) 编辑

[置顶] Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vaccine Development （解读人：张聪敏）

摘要：文献名：Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vacc 阅读全文

posted @ 2020-02-18 09:43 ilifeiscience 阅读(206) 评论(0) 推荐(0) 编辑

[置顶] Data-independent acquisition mass spectrometry in metaproteomics of gut microbiota - implementation and computational analysis DIA技术在肠道宏蛋白质组研究中的方法实现和数据分析（解读人：闫克强）

摘要：文献名：Data-independent acquisition mass spectrometry in metaproteomics of gut microbiota - implementation and computational analysis（DIA技术在肠道宏蛋白质组研究中的方法阅读全文

posted @ 2020-02-10 21:01 ilifeiscience 阅读(503) 评论(0) 推荐(0) 编辑

[置顶] Systematic comparison of strategies for the enrichment of lysosomes by data independent acquisition 通过DIA技术系统比较各溶酶体富集策略（解读人：王欣然）

摘要：文献名：Systematic comparison of strategies for the enrichment of lysosomes by data independent acquisition（通过DIA技术系统比较各溶酶体富集策略）期刊名：Journal of Proteome R 阅读全文

posted @ 2020-02-10 20:58 ilifeiscience 阅读(604) 评论(0) 推荐(0) 编辑

[置顶] Untargeted lipidomics reveals specific lipid abnormality in nonfunctioning human pituitary adenomas 非靶向脂质组学揭示非功能人类脑垂体瘤中的特异性脂质（解读人：胡丹丹）

摘要：文献名：Untargeted lipidomics reveals specific lipid abnormality in nonfunctioning human pituitary adenomas（非靶向脂质组学揭示非功能人类脑垂体瘤中的特异性脂质）期刊名：Journal of Prot 阅读全文

posted @ 2020-02-10 20:51 ilifeiscience 阅读(433) 评论(0) 推荐(0) 编辑

[置顶] Journal of Proteome Research | 人类牙槽骨蛋白的蛋白质组学和n端分析:改进的蛋白质提取方法和LysargiNase消化策略增加了蛋白质组的覆盖率和缺失蛋白的识别 | (解读人：卜繁宇)

摘要：文献名：Proteomic and N-Terminomic TAILS Analyses of Human Alveolar Bone Proteins: Improved Protein Extraction Methodology and LysargiNase Digestion Strat 阅读全文

posted @ 2019-12-30 09:26 ilifeiscience 阅读(491) 评论(0) 推荐(0) 编辑

[置顶] Journal of Proteome Research | SAAVpedia: identification, functional annotation, and retrieval of single amino acid variants for proteogenomic interpretation | SAAV的识别、功能注释和检索 | (解读人：徐洪凯)

摘要：文献名：SAAVpedia: identification, functional annotation, and retrieval of single amino acid variants for proteogenomic interpretation（SAAVpedia:蛋白质基因组解释的阅读全文

posted @ 2019-12-27 16:18 ilifeiscience 阅读(397) 评论(0) 推荐(0) 编辑

2020年8月11日

Comparative Glycoproteomic Profiling of Human Body Fluid between Healthy Controls and Patients with Papillary Thyroid Carcinoma（健康对照与乳头状甲状腺癌患者之间人体体液的糖蛋白质组学比较。）

摘要：文献名：Comparative Glycoproteomic Profiling of Human Body Fluid between Healthy Controls and Patients with Papillary Thyroid Carcinoma（健康对照与乳头状甲状腺癌患者之间人体阅读全文

posted @ 2020-08-11 12:19 ilifeiscience 阅读(164) 评论(0) 推荐(0) 编辑

Detergent-Free Simultaneous Sample Preparation Method for Proteomics and Metabolomics (一种无变性剂的同时制备蛋白质组和代谢组样品的方法)

摘要：文献名：Detergent-Free Simultaneous Sample Preparation Method for Proteomics and Metabolomics (一种无变性剂的同时制备蛋白质组和代谢组样品的方法) 期刊名：Journal of proteome research 阅读全文

posted @ 2020-08-11 12:16 ilifeiscience 阅读(185) 评论(0) 推荐(0) 编辑

SWATH-MS Analysis of FFPE Tissues Identifies Stathmin as a Potential Marker of Endometrial Cancer in Patients Exposed to Tamoxifen

摘要：文献名：SWATH-MS Analysis of FFPE Tissues Identifies Stathmin as a Potential Marker of Endometrial Cancer in Patients Exposed to Tamoxifen doi: 10.1021/ac 阅读全文

posted @ 2020-08-11 12:14 ilifeiscience 阅读(240) 评论(0) 推荐(0) 编辑

Plasma-derived EV Phosphoproteomics through Chemical Affinity Purification（基于化学亲和纯化方法研究血浆来源胞外囊泡的磷酸化蛋白质组）

摘要：文献名：Plasma-derived EV Phosphoproteomics through Chemical Affinity Purification（基于化学亲和纯化方法研究血浆来源胞外囊泡的磷酸化蛋白质组）期刊名：Journal of proteome research 发表时间：（20 阅读全文

posted @ 2020-08-11 12:10 ilifeiscience 阅读(515) 评论(0) 推荐(0) 编辑

2020年6月8日

摘要：文献名：Sex- and Age-Related Metabolic Characteristics of Serum Free Fatty Acids in Healthy Chinese Adults（中国健康成年人血清游离脂肪酸的性别和年龄相关代谢表征）期刊名：Journal of prot 阅读全文

posted @ 2020-06-08 14:43 ilifeiscience 阅读(1593) 评论(0) 推荐(0) 编辑

2020年6月5日

Accelerated Lysis and Proteolytic Digestion of Biopsy-level Fresh Frozen and FFPE Tissue Samples Using Pressure Cycling Technology （压力循环系统可加速新鲜冻存和福尔马林固定样本的裂解及蛋白酶解）【分享人：张雨星】

摘要：题目：Accelerated Lysis and Proteolytic Digestion of Biopsy-level Fresh Frozen and FFPE Tissue Samples Using Pressure Cycling Technology （压力循环系统可加速新鲜冻存和福阅读全文

posted @ 2020-06-05 10:32 ilifeiscience 阅读(440) 评论(0) 推荐(0) 编辑

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