[转载]蛋白质序列数据库

3. Protein Sequence Databases

 

3.1. General sequence databases

 

EXProt

Sequences of proteins with experimentally verified function

http://wwwNaNbi.kun.nl/EXProt/

MIPS resources

Munich Information Center for Protein Sequences databases

http://mips.gsf.de/

NCBI Protein database

All protein sequences: translated from GenBank and imported from other protein databases

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Protein

PA-GOSUB

Protein sequences from model organisms, GO assignment and subcellular localization

http://www.cs.ualberta.ca/~bioinfo/PA/

PIR

Protein Information Resource

http://pir.georgetown.edu

PRF

Protein research foundation database of peptides

http://www.prf.or.jp/en/index.shtml

TCDB

Transporter protein classification database

http://www.tcdb.org/

UniParc

UniProt archive, a repository of all protein sequences

http://www.uniprot.org/database/archive.shtml

UniProt

Universal Protein knowledgebase, combined information from Swiss-Prot, TrEMBL, and PIR

http://www.uniprot.org

UniProtKB\Swiss-Prot

Formerly SwissProt, part of the UniProt knowledgebase

http://www.expasy.org/sprot

UniProtKB\TrEMBL

Now UniProt/TrEMBL, part of the UniProt knowledgebase

http://www.uniprot.org/database/knowledgebase.shtml

UniRef

Clustered sets of related sequences from UniProt

http://www.uniprot.org/database/nref.shtml

UniSave

UniProtKB Sequence/Annotation Version Archive

http://www.ebi.ac.uk/uniprot/unisave/

3.2. Protein properties

 

AAindex

Physicochemical properties of amino acids

http://www.genome.ad.jp/aaindex/

BindingDB

Binding affinities of protein-ligand and other complexes

http://www.bindingdb.org/bind/index.jsp

CyBase

Proteins with cyclic backbones

http://research1t.imb.uq.edu.au/cybase

dbPTM

Information on post-translational modification of proteins

http://dbptm.mbc.nctu.edu.tw/

iProLINK

Annotated literature sources for protein features and names

http://pir.georgetown.edu/iprolink

MALISAM

Manual alignments for structurally analogous motifs in proteins

http://prodata.swmed.edu/malisam

MegaMotifbase

Structural motifs in protein families and superfamilies

http://caps.ncbs.res.in/MegaMotifbase/index.html

PIDD

Protein inter-atomic distances database

http://pidd.math.iastate.edu

PINT

Protein-protein interactions thermodynamic database

http://pintdb.dyndns.org/index.html

PPD

Experimentally-determined protein pKa values

http://www.jenner.ac.uk/ppd/

PPT-DB

Protein Property Prediction and Testing Database

http://redpoll.pharmacy.ualberta.ca/PPT_DB/public_html/PPT_main.html

ProTherm

Thermodynamic data for wild-type and mutant proteins

http://gibk26.bse.kyutech.ac.jp/jouhou/protherm/protherm.html

PRTAD

Protein residue torsion angle database

http://www.math.iastate.edu/prtad

REFOLD

Experimental data on protein refolding and purification

http://refold.med.monash.edu.au

3.3. Protein localization and targeting

 

DBSubLoc -

Database of protein Subcellular Localization

http://www.bioinfo.tsinghua.edu.cn/dbsubloc.html

eSLDB

eukaryotic proteins Subcellular Localization Database

http://gpcr.biocomp.unibo.it/esldb

InterFil

Human Intermediate Filament database

http://www.interfil.org

LOCATE

Subcellular localization of mouse proteins

http://locate.imb.uq.edu.au/

MiCroKit

Midbody, Centrosome and Kinetochore proteins

http://bioinformatics.lcd-ustc.org/microkit/

MitoDrome

Nuclear-encoded mitochondrial proteins of Drosophila

http://www2.ba.itb.cnr.it/MitoDrome/

MitoRes

Nuclear genes coding for mitochondrial proteins

http://www2.ba.itb.cnr.it/MitoNuc/

NESbase

Nuclear export signals database

http://www.cbs.dtu.dk/databases/NESbase

NLSdb

Nuclear localization signals

http://cubic.bioc.columbia.edu/db/NLSdb/

NMPdb

Nuclear matrix associated proteins database

http://www.rostlab.org/db/NMPdb/

NOPdb:

Nucleolar proteome database

http://www.lamondlab.com/NOPdb/

NPD

Nuclear Protein Database

http://npd.hgu.mrc.ac.uk

Nuclear Receptor Resource

Nuclear receptor superfamily

http://nrr.georgetown.edu/NRR/nrrhome.htm

NUREBASE

Nuclear hormone receptors database

http://www.ens-lyon.fr/LBMC/laudet/nurebase/nurebase.html

NURSA

Nuclear receptor signaling atlas

http://www.nursa.org

PSORTdb

Protein subcellular localization in bacteria

http://db.psort.org/

Secreted Protein DB

Secreted proteins from human, mouse and rat

http://spd.cbi.pku.edu.cn

SUBA

Subcellular localisation of Arabidopsis proteins

http://www.suba.bcs.uwa.edu.au/

THGS

Transmembrane Helices in Genome Sequences

http://pranag.physics.iisc.ernet.in/thgs/

TopDB

Topology Data Bank of transmembrane proteins

http://topdb.enzim.hu

Transmembrane Protein Database

Transmembrane proteins with experimentally-characterized transmembrane topologies

http://bioinfo.si.hirosaki-u.ac.jp/~TMPDB/

3.4. Protein sequence motifs and active sites

 

ASC

Active Sequence Collection

http://bioinformatica.isa.cnr.it/ASC/

Blocks

Alignments of conserved regions in protein families

http://blocks.fhcrc.org

COMe

Co-Ordination of Metals etc.

http://www.ebi.ac.uk/come/

CoPS

Comprehensive peptide signature database

http://cops.igib.res.in/copsv2/index.html

CSA

Catalytic Site Atlas

http://www.ebi.ac.uk/thornton-srv/databases/CSA/

eBLOCKS

Highly conserved protein sequence blocks

http://fold.stanford.edu/eblocks/acsearch.html

eF-site

Electrostatic surface of Functional site

http://ef-site.protein.osaka-u.ac.jp/eF-site

eMOTIF

Protein sequence motif determination and searches

http://motif.stanford.edu/emotif

FireDB

Functionally important residues in protein structures

http://firedb.bioinfo.cnio.es/

InterPro

Integrated resource of protein families, domains and functional sites

http://www.ebi.ac.uk/interpro

Metalloprotein Site DB

Metal-binding sites in metalloproteins

http://metallo.scripps.edu/

O-GLYCBASE

O- and C-linked glycosylation sites in proteins

http://www.cbs.dtu.dk/databases/OGLYCBASE/

PDBSite

3D structure of protein functional sites

http://srs6.bionet.nsc.ru/srs6bin/cgi-bin/wgetz?-page+LibInfo+-newId+-lib+PDBSite

Phospho.ELM

S/T/Y protein phosphorylation sites (former PhosphoBase)

http://phospho.elm.eu.org/

Phospho3D

3D structures of protein phosphorylation sites

http://cbm.bio.uniroma2.it/p3d/

PRINTS

Hierarchical gene family fingerprints

http://umber.sbs.man.ac.uk/dbbrowser/PRINTS/

PROMISE

Prosthetic centers and metal ions in protein active sites

http://metallo.scripps.edu/PROMISE/

ProRule

Functional and structural information on PROSITE profiles

http://www.expasy.org/prosite/prorule.html

PROSITE

Biologically-significant protein patterns and profiles

http://www.expasy.org/prosite

ProTeus

Signature sequences at the protein N- and C-termini

http://www.proteus.cs.huji.ac.il

SitesBase

Known ligand binding sites in the PDB

http://www.modelling.leeds.ac.uk/sb/

3.5. Protein domain databases; protein classification

ADDA

Database of protein domain classification

http://ekhidna.biocenter.helsinki.fi/sqgraph/pairsdb

BAliBASE

Benchmark database for comparison of multiple sequence alignments

http://www-igbmc.u-strasbg.fr/BioInfo/BAliBASE2/index.html

Benchmark

Protein classification benchmark collection: training/test sets for machine learning

http://net.icgeb.org/benchmark/

BIOZON

Database of gene and protein familiy classification

http://biozon.org

CDD

Conserved domain database, includes protein domains from Pfam, SMART, COG and KOG databases

http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml

CluSTr

Clusters of UniProt Knowledgebase and IPI proteins

http://www.ebi.ac.uk/clustr/

COG

Clusters of orthologous groups of proteins

http://www.ncbi.nlm.nih.gov/COG

DomIns

Database of Domain Insertions

http://www.domins.org/

eggNOG

Evolutionary genealogy of genes: Non-supervised Orthologous Groups

http://eggnog.embl.de

EPGD

Eukaryotic Paralog Group Database

http://epgd.biosino.org:8080/EPGD/

EVEREST

Automatically generated protein domain families

http://www.everest.cs.huji.ac.il

FunShift

Functional divergence between the subfamilies of a protein domain family

http://FunShift.cgb.ki.se

FusionDB

Database of bacterial and archaeal gene fusion events

http://www.igs.cnrs-mrs.fr/FusionDB/

Hits

Database of protein domains and motifs

http://hits.isb-sib.ch

HSSP

Homology-derived structures of proteins

http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-page+LibInfo+-lib+HSSP

InterDom

Putative protein domain interactions

http://interdom.i2r.a-star.edu.sg/

iProClass

Integrated protein classification database

http://pir.georgetown.edu/iproclass/

MulPSSM

Multiple PSSMs of structural and sequence families

http://hodgkin.mbu.iisc.ernet.in/~mulpssm

PairsDB

Pairwise alignments of all sequences in UniProt

http://pairsdb.csc.fi

PALI

Phylogeny and alignment of homologous protein structures

http://pauling.mbu.iisc.ernet.in/~pali

PANTHER

Protein sequence evolution mapped to functions and pathways

http://www.pantherdb.org

Pfam

Protein families: Multiple sequence alignments and profile hidden Markov models of protein domains

http://pfam.sanger.ac.uk/

PhyloFacts

Phylogenomic analysis of protein families

http://phylogenomics.berkeley.edu/phylofacts/

PIRSF

Family/superfamily classification of whole proteins

http://pir.georgetown.edu/pirsf/

ProDom

Protein domain families

http://prodom.prabi.fr/

ProtoMap

Hierarchical classification of Swiss-Prot proteins

http://protomap.cornell.edu

ProtoNet

Hierarchical clustering of Swiss-Prot proteins

http://www.protonet.cs.huji.ac.il/

SBASE

Protein domain sequences and tools

http://www.icgeb.org/sbase

SIMAP

Similarity matrix of proteins: precomputed similarity data

http://mips.gsf.de/simap/

SISYPHUS

Structural alignments for proteins with non-trivial relationships

http://sisyphus.mrc-cpe.cam.ac.uk

SMART

Simple modular architecture research tool: signalling, extracellular and chromatin-associated protein domains

http://smart.embl-heidelberg.de

SUPFAM

Grouping of sequence families into superfamilies

http://pauling.mbu.iisc.ernet.in/~supfam

TIGRFAMs

TIGR protein families adapted for functional annotation

http://www.tigr.org/TIGRFAMs

 

 

3.6. Databases of individual protein families

ABCdb

Archaeal and bacterial ABC transporter database

http://www-abcdb.biotoul.fr

Aminoacyl-tRNA synthetases database

Aminoacyl-tRNA synthetase database

http://rose.man.poznan.pl/aars/index.html

Animal Toxin DB

Database of animal toxins

http://protchem.hunnu.edu.cn/toxin

ARAMEMNON

Arabidopsis thaliana membrane proteins and transporters

http://aramemnon.botanik.uni-koeln.de

BACTIBASE

Database of bacteriocin natural antimicrobial peptides

http://www.pfba-lab.org/bactibase

BacTregulators

Transcriptional regulators of AraC and TetR families

No longer maintained

BANMOKI

Database of bacterial nucleoside monophosphate kinases

http://www.ces.clemson.edu/compbio/databases/kinases

ChromDB

Chromatin-associated proteins in a broad range of organisms

http://www.chromdb.org

cpnDB

Chaperonin database

http://cpndb.cbr.nrc.ca/

CREMOFAC

Database of chromatin remodeling factors

http://www.jncasr.ac.in/cremofac/

CSDBase

Cold Shock Domain database

http://www.chemie.uni-marburg.de/~csdbase/

CyMoBase

Cytoskeletal and motor proteins database

http://www.motorprotein.de/cymobase

DB-PABP

Experimentally characterized polyanion-binding proteins

http://ppa.bcf.ku.edu/DB_PABP/

DCCP

Database of Copper-Chelating Proteins

http://sdbi.sdut.edu.cn/DCCP/en/index.php

Defensins Knowledgebase

Antimicrobial peptides of the defensin family

http://defensins.bii.a-star.edu.sg/

DExH/D Family DB

DEAD-box, DEAH-box and DExH-box proteins

http://www.helicase.net/dexhd/dbhome.htm

DSD

Database of dehydrogenase stereospecificities

http://www.jenner.ac.uk/DSD

Endogenous GPCR List

G protein-coupled receptors; expression in cell lines

http://www.tumor-gene.org/GPCR/gpcr.html

EROP-Moscow

Database of Endogenous Regulatory OligoPeptides

http://erop.inbi.ras.ru

ESTHER

Esterases and other alpha/beta hydrolase enzymes

http://bioweb.ensam.inra.fr/ESTHER/general?what=index

FUNPEP

Low-complexity peptides capable of forming amyloid plaque

http://wwwNaNbi.kun.nl/swift/FUNPEP/gergo/

GPCRDB

G protein-coupled receptors database

http://www.gpcr.org/7tm/

gpDB

G-protein database: G-proteins and their interaction with GPCRs

http://bioinformatics.biol.uoa.gr/gpDB

Heme Protein DB

Heme protein structure, heme type, axial ligands, and heme protein reduction potential (Em) values

http://heme.chem.columbia.edu/heme.php

Histone Database

Histone fold sequences and structures

http://research.nhgri.nih.gov/histones/

HIV RT and Protease Sequence Database

HIV reverse transcriptase and protease sequences

http://hivdb.stanford.edu

Homeobox Page

Homeobox proteins, classification, and evolution

http://www.biosci.ki.se/groups/tbu/homeo.html

Homeodomain Resource

Homeodomain sequences, structures, and related genetic and genomic information

http://research.nhgri.nih.gov/homeodomain/

InBase

Inteins (protein splicing elements) database: properties, sequences, bibliography

http://www.neb.com/neb/inteins.html

KinG

Kinases in Genomes: Ser/Thr/Tyr kinases encoded in the completely sequenced genomes

http://hodgkin.mbu.iisc.ernet.in/~king

Knottin database

Database of knottins, small proteins with an unusual "disulfide through disulfide" knot

http://knottin.cbs.cnrs.fr/

LGICdb

Ligand-gated ion channel subunit sequences database

http://www.pasteur.fr/recherche/banques/LGIC/LGIC.html

Lipase Engineering DB

Sequence, structure and function of lipases and esterases

http://www.led.uni-stuttgart.de/

LOX-DB

Mammalian, invertebrate, plant and fungal lipoxygenases

http://www.dkfz-heidelberg.de/spec/lox-db/

MEROPS

Database of proteolytic enzymes (peptidases)

http://merops.sanger.ac.uk/

NORINE

Database of nonribosomal peptides

http://bioinfo.lifl.fr/norine/

NucleaRDB

Nuclear receptor superfamily

http://www.receptors.org/NR/

Olfactory Receptor DB

Sequences for olfactory receptor-like molecules

http://senselab.med.yale.edu/senselab/ordb/

Peptaibol

Peptaibol (antibiotic peptide) sequences

http://www.cryst.bbk.ac.uk/peptaibol/

PhytoProt

Clusters of (predicted) plant proteins

http://urgi.versailles.inra.fr/phytoprot/

PLANT-PIs

Plant protease inhibitors

http://bighost.area.ba.cnr.it/PLANT-Pis

PlantsP/PlantsT

Plant proteins involved in phosphorylation and transport

http://plantsp.sdsc.edu

PLPMDB

Pyridoxal-5'-phosphate dependent enzymes mutations

http://www.studiofmp.com/plpmdb/

ProLysED

Database of bacterial protease systems

http://genome.ukm.my/prolyses/

Prolysis

Proteases and natural and synthetic protease inhibitors

http://delphi.phys.univ-tours.fr/Prolysis/

Protein kinase resource

Protein kinase resource: sequences, enzymology, genetics and molecular and structural properties

http://www.kinasenet.org/pkr/

REBASE

Restriction enzymes and associated methylases

http://rebase.neb.com/rebase/rebase.html

RNAse P Database

Ribonuclease P sequences, alignments and structures

http://www.mbio.ncsu.edu/RNaseP/home.html

RNRdb

Ribonucleotide reductase database

http://rnrdb.molbio.su.se/

RPG

Ribosomal Protein Gene database

http://ribosome.miyazaki-med.ac.jp/

RTKdb

Receptor Tyrosine Kinase database

http://pbil.univ-lyon1.fr/RTKdb/

SDAP

Structural database of allergenic proteins and food allergens

http://fermi.utmb.edu/SDAP

SelenoDB

Database of selenoprotein genes, proteins and SECIS elements

http://www.selenodb.org/

SENTRA

Sensory signal transduction proteins

http://compbio.mcs.anl.gov/sentra/

SEVENS

7-transmembrane helix receptors (G-protein-coupled)

http://sevens.cbrc.jp/1.20/

Telomerase database

Sequences and structures of the RNA and protein subunits of telomerase, mutations of telomerase components

http://telomerase.asu.edu

TransportDB

Predicted membrane transporters in complete genomes, classified according to the TC classification system

http://www.membranetransport.org

VKCDB

Voltage-gated K+ Channel Database

http://vkcdb.biology.ualberta.ca/

Wnt Database

Wnt proteins and phenotypes

http://www.stanford.edu/~rnusse/wntwindow.html

 



http://blog.sciencenet.cn/blog-748683-886125.html  此文来自科学网潘兴亮博客,转载请注明出处。 

posted @ 2016-04-08 21:11  Jarning_Gau  阅读(745)  评论(0)    收藏  举报