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| The Bicoid Morphogen Papers (I): Account from CNV Christiane N. Nüsslein-Volhard |
S1-5 | |||
| The Bicoid Morphogen Papers (II): Account from Wolfgang Driever Wolfgang Driever |
S7-9 | |||
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A Gradient of bicoid Protein in Drosphila Embryos W. Driever and C. Nüsslein-Volhard |
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| The bicoid Protein Determines Position in the Drosophila Embryo in a Concentration-Dependent Manner W. Driever and C.Nüsslein-Volhard |
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| 23 Genes, 23 Years Later Randy Schekman and Peter Novick |
S13-15 | |||
| Vesicle Traffic In Vitro William E. Balch |
S17-19 | |||
| Identification of 23 Complementation Groups Required for Post-translational Events in the Yeast Secretory Pathway P. Novick, C. Field and R. Schekman |
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| Reconstitution of the Transport of Protein between Successive Compartments of the Golgi Measured by the Coupled Incorporation of N-Acetylglucosamine W.E. Balch, W.G. Dunphy, W.A. Braell, and J.E. Rothman |
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| Snails, Swiss, and Serum: The Solution for Rac 'n' Rho Anne J. Ridley and Alan Hall |
S23-25 | |||
| The Small GTP-Binding Protein rho Regulates the Assembly of Focal Adhesions and Actin Stress Fibers in Response to Growth Factors A.J. Ridley and A. Hall |
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| The Small GTP-Binding Protein rac Regulates Growth Factor–Induced Membrane Ruffling A.J. Ridley, H.F. Paterson, C.L. Johnston, D. Diekmann, and A. Hall |
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| Ubiquitin As a Central Cellular Regulator Daniel Finley, Aaron Ciechanover, and Alexander Varshavsky |
S29-32 | |||
| Thermolability of Ubiquitin-Activating Enzyme from the Mammalian Cell Cycle Mutant ts85 D. Finley, A. Ciechanover, and A. Varshavsky |
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| Ubiquitin Dependence of Selective Protein Degradation Demonstrated in the Mammalian Cell Cycle Mutant ts85 A. Ciechanover, D. Finley, and A. Varshavsky |
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| The Discovery of Tyrosine Phosphorylation: It's All in the Buffer! Tony Hunter and Walter Eckhart |
S35-39 | |||
| ZIP Codes for Delivering SH2 Domains Zhou Songyang and Lewis C. Cantley |
S41-43 | |||
| Structure and Specificity of the SH2 Domain Gabriel Waksman and John Kuriyan |
S45-48 | |||
| An Activity Phosphorylating Tyrosine in Polyoma T Antigen Immunoprecipitates W. Eckhart, M.A. Hutchinson and T. Hunter |
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| SH2 Domains Recognize Specific Phosphopeptide Sequences Z. Songyang, S.E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W.G. Haser, F. King, T. Roberts, S. Ratnofsky, R.J. Lechleider, B.G. Neel, R.B. Birge, J.E. Fajardo, M.M. Chou, H. Hanafusa, B. Schaffhausen, and L.C. Cantley |
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| Binding of a High Affinity Phosphotyrosyl Peptide to the Src SH2 Domain: Crystal Structures of the Complexed and Peptide-free Forms G. Waksman, S.E. Shoelson, N. Pant, D. Cowburn, and J. Kuriyan |
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| A First Insight into the Molecular Mechanisms of Apoptosis Junying Yuan and H. Robert Horvitz |
S53-56 | |||
| Mitochondrial Activation of Apoptosis Peng Li, Deepak Nijhawan, and Xiaodong Wang |
S57-59 | |||
| The C. elegans Cell Death Gene ced-3 Encodes a Protein Similar to Mammalian Interleukin-1β-Converting Enzyme J. Yuan, S. Shaham, S. Ledoux, H.M. Ellis, and H.R. Horvitz |
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| Cytochrome c and dATP-Dependent Formation of ApaF-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, E.S. Alnemri, and X. Wang |
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| The Discovery of Cyclin (I) Tim Hunt |
S63-64 | |||
| The Discovery of Cyclin (II) Tom Evans |
S65 | |||
| Cyclin: A Protein Specified by Maternal mRNA in Sea Urchin Eggs That Is Destroyed at Each Cleavage Division T. Evans, E.T. Rosenthal, J. Youngblom, D. Distel, and T. Hunt |
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| P53 is a Tumor Suppressor Gene Arnold J. Levine, Cathy A. Finlay, and Philip W. Hinds |
S67-69 | |||
| The p53 Proto-Oncogene Can Act as a Suppressor of Transformation C.A. Finlay, P.W. Hinds, and A.J. Levine |
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| Two “What If” Experiments Mark Ptashne |
S71-72 | |||
| Building an Artificial Regulatory System to Understand a Natural One Roger Brent |
S73-74 | |||
| Actively Seeking Activating Sequences Jun Ma |
S75-76 | |||
| A Eukaryotic Transcriptional Activator Bearing the DNA Specificity of a Prokaryotic Repressor R. Brent and M. Ptashne |
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| A New Class of Yeast Transcriptional Activators Jun Ma and Mark Ptashne |
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| Seeing Is Believing Pierre Oudet and Pierre Chambon |
S79-80 | |||
| Electron Microscopic and Biochemical Evidence that Chromatin Structure Is a Repeating Unit P. Oudet, M. Gross-Bellard, and P. Chambon |
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| Tracking Telomerase Carol W. Greider and Elizabeth H. Blackburn |
S83-86 | |||
| Identification of a Specific Telomere Terminal Transferase Activity in Tetrahymena Extracts C.W. Greider and E.H. Blackburn |
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| A Short History of a Short RNA Rosalind Lee, Rhonda Feinbaum, and Victor Ambros |
S89-92 | |||
| The 20 Years It Took to Recognize the Importance of Tiny RNAs Gary Ruvkun, Bruce Wightman, and Ilho Ha |
S93-96 | |||
| The C. elegans Heterochronic Gene lin-4 Encodes Small RNAs with Antisense Complementarity to lin-14 R.C. Lee, R.L. Feinbaum, and V. Ambros |
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| Posttranscriptional Regulation of the Heterochronic Gene lin-14 by lin-4 Mediates Temporal Pattern Formation in C. elegans B. Wightman, I. Ha, and G. Ruvkun |
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| That Great Time in Basel Susumu Tonegawa |
S99-101 | |||
| Uncovering the V(D)J Recombinase David G. Schatz and David Baltimore |
S103-106 | |||
| A Complete Immunoglobulin Gene Is Created by Somatic Recombination C. Brack, M. Hirama, R. Lenhard-Schuller and S. Tonegawa |
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| The V(D)J Recombination Activating Gene, RAG-1 D.G. Schatz, M.A. Oettinger, and D. Baltimore |
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| Early Evidence That a Protease-Resistant Protein Is an Active Component of the Infectious Prion Stanley B. Prusiner |
S109 | |||
| A Mouse to Remember Charles Weissmann and Hansruedi Büeler |
S111-113 | |||
| A Protease-Resistant Protein Is a Structural Component of the Scrapie Prion M.P. McKinley, D.C. Bolton, and S.B. Prusiner |
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| Mice Devoid of PrP Are Resistant to Scrapie H. Büeler, A. Aguzzi, A. Sailer, R.-A. Greiner, P. Autenried, M. Aguet, and C. Weissmann |
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| The Search for Odorant Receptors Linda B. Buck |
S117-119 | |||
| A Novel Multigene Family May Encode Odorant Receptors: A Molecular Basis for Odor Recognition L. Buck and R. Axel |
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| A Thin Commentary on a Fat Receptor Louis A. Tartaglia and Robert I. Tepper |
S121-122 | |||
| Identification and Expression Cloning of a Leptin Receptor, OB-R L.A. Tartaglia, M. Dembski, X. Weng, N. Deng, J. Culpepper, R. Devos, G.J. Richards, L.A. Campfield, F.T. Clark, J. Deeds, C. Muir, S. Sanker, A. Moriarty, K.J. Moore, J.S. Smutko, G.G. Mays, E.A. Woolf, C.A. Monroe, and R.I. Tepper | ||||
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