fine-mapping | 精准映射

待看的paper:Strategies for fine-mapping complex traits

assign well-calibrated probabilities of causality to candidate variants, known as fine-mapping.

fine mapping是GWAS之后的精细分析,因为GWAS可能会鉴定出来很多variation,但不知道哪些是casual的,fine mapping就是借助统计学的模型(贝叶斯等)来推测出哪些才是真正的casual variation。

 

posted @ 2018-06-25 16:09 Bioinformatics 阅读(...) 评论(...) 编辑 收藏
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